Drawing a different picture with pencil lead as matrix-assisted laser desorption/ionization matrix for fullerene derivatives

European Journal of Mass Spectrometry
Leanne C NyeThomas Drewello

Abstract

Inspired by reports on the use of pencil lead as a matrix-assisted laser desorption/ionization matrix, paving the way towards matrix-free matrix-assisted laser desorption/ionization, the present investigation evaluates its usage with organic fullerene derivatives. Currently, this class of compounds is best analysed using the electron transfer matrix trans-2-[3-(4-tert-butylphenyl)-2-methyl-2-propenylidene] malononitrile (DCTB), which was employed as the standard here. The suitability of pencil lead was additionally compared to direct (i.e. no matrix) laser desorption/ionization-mass spectrometry. The use of (DCTB) was identified as the by far gentler method, producing spectra with abundant molecular ion signals and much reduced fragmentation. Analytically, pencil lead was found to be ineffective as a matrix, however, appears to be an extremely easy and inexpensive method for producing sodium and potassium adducts.

References

Dec 18, 2002·Journal of the American Society for Mass Spectrometry·Dorina FatiHartmut Hungerbühler
Feb 25, 2006·Rapid Communications in Mass Spectrometry : RCM·Claudie BlackJulie Herniman
Jul 13, 2006·The Journal of Physical Chemistry. a·Alexey V StreletskiiOlga V Boltalina
Jul 21, 2006·The Journal of Physical Chemistry. B·Yury V Vasil'evThomas Drewello
Sep 13, 2006·Mass Spectrometry Reviews·Dominic S Peterson
Dec 26, 2006·Journal of Biochemical and Biophysical Methods·M Najam-ul-HaqG K Bonn
Jun 23, 2010·Analytical Chemistry·Xiaoli DongYinsheng Wang
Jun 12, 2014·Mass Spectrometry Reviews·Taryn GuinanNicolas H Voelcker

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