Drift of the Bowman Hemedex® cerebral blood flow monitor between calibration cycles

Acta Neurochirurgica. Supplement
Stefan WolfP Horn

Abstract

Since its introduction into clinical practice, the Bowman Hemedex® regional cerebral blood flow (CBF) monitor has provided a valuable tool for the bedside assessment of CBF in neurointensive care. The purpose of our study was to estimate the accuracy of CBF measurements between automatically performed self-calibration cycles at regular intervals. We analyzed data from 75 CBF probes, predominantly implanted into patients after severe subarachnoid hemorrhage. Automatic recalibration of the regional CBF device was performed every 30 min. CBF data were averaged once per minute and the measurement cycles pooled. Statistical analysis was performed with generalized additive modeling and bootstrapping methods. Mean regional CBF was 24 mL/100 g/min after calibration and showed a mean drift of 2.3 mL/100 g/min per measurement cycle (p < 0.001). In every patient, the drift over the measurement cycle followed an exponential trend, with large heterogeneity between patients (-3.67 to 12.0 mL/100 g/min). A highly significant difference in drift was found for the internal software versions of the monitoring devices (p < 0.001). Data from the Bowman Hemedex® regional CBF monitor shows an upward measurement drift of clinically relevant magnitude...Continue Reading

Citations

Apr 25, 2014·IEEE Transactions on Bio-medical Engineering·Daniel SvenkesonHoward Yonas
Sep 18, 2016·Neurosurgery Clinics of North America·Christos Lazaridis, Claudia S Robertson
Nov 2, 2017·Neurosurgical Focus·Saurabh SinhaRamani Balu
May 16, 2019·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Wesley B BakerW Andrew Kofke

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