Driving performance of stable outpatients with depression undergoing real-world treatment

Psychiatry and Clinical Neurosciences
Akemi MiyataNorio Ozaki

Abstract

Although the effects of psychotropics on driving ability have received much attention, little research is available on driving performance of stable outpatients with depression undergoing real-world treatment. This observational study investigated driving performance, cognitive functions, and depressive symptomatology of partly remitted outpatients with depression under daily-practice psychopharmacologic treatment. Seventy stable outpatients with depression and 67 healthy volunteers were enrolled. Patients' prescriptions were not controlled in order to capture the real-world treatment environment. Participants underwent three driving tasks - road-tracking, car-following, and harsh-braking - using a driving simulator, and three cognitive tasks - Continuous Performance Test, Wisconsin Card Sorting Test, and Trail-Making Test. The Symptom Assessment Scale - Structured Interview Guide for the Hamilton Depression Rating Scale, Beck Depression Inventory-II, Social Adaptation Self-Evaluation Scale, and Stanford Sleepiness Scale were also completed. Although many patients received various pharmacologic treatments, there were no significant differences in the three driving tasks between outpatients with depression and healthy controls. ...Continue Reading

References

Oct 1, 1992·American Journal of Epidemiology·W A RayM D Decker
Aug 1, 1988·Archives of General Psychiatry·J B Williams
Jul 1, 1973·Psychophysiology·E HoddesW C Dement
Jan 1, 1984·British Journal of Clinical Pharmacology·J F O'Hanlon
Jul 2, 1982·Science·J F O'HanlonJ B Riemersma
Mar 1, 1995·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·H W Robbe, J F O'Hanlon
Dec 1, 1996·Journal of Personality Assessment·A T BeckW Ranieri
Apr 1, 1997·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·M BoscV Polin
Mar 7, 2001·The British Journal of Psychiatry : the Journal of Mental Science·M P AustinG M Goodwin
Nov 20, 2003·Neuroscience Letters·Yuji UchiyamaNorihiro Sadato
Aug 2, 2005·Accident; Analysis and Prevention·Fridulv Sagberg
Mar 9, 2006·Journal of Affective Disorders·Eric L BulmashColin M Shapiro
Jul 26, 2006·Psychopharmacology·Marleen WingenJeroen A J Schmitt
Sep 2, 2006·The American Journal of Psychiatry·Ronald C KesslerPhilip S Wang
Oct 19, 2006·Psychiatry Research·Judith JaegerSara Davis-Conway
Jan 2, 2007·The Journal of Clinical Psychiatry·Alexander BrunnauerHans-Jürgen Möller
Jan 23, 2009·Primary Care Companion to the Journal of Clinical Psychiatry·Carlos De Las Cuevas, Emilio J Sanz
Feb 11, 2009·The Journal of Clinical Psychiatry·Alexander BrunnauerHans-Jürgen Möller
Dec 9, 2009·Neuroscience Letters·Seiko MiyataYasuo Koike
Jan 6, 2010·Archives of General Psychiatry·Ramin Mojtabai, Mark Olfson
Mar 20, 2010·CNS Drugs·Tracy L GreerMadhukar H Trivedi
May 22, 2010·Journal of Psychosomatic Research·Toshi A Furukawa
Dec 18, 2010·Journal of Affective Disorders·Bo Jacob HasselbalchLars Vedel Kessing
Apr 20, 2011·British Journal of Clinical Pharmacology·Silvia RaveraLolkje T W de Jong-van den Berg
Sep 13, 2012·The Journal of Clinical Psychiatry·Ludivine OrriolsUNKNOWN CESIR Research Group
Sep 14, 2012·British Journal of Clinical Pharmacology·Chia-Ming ChangHui-Ju Tsai
Oct 4, 2012·Journal of Affective Disorders·Christine M WickensJürgen Rehm
Feb 4, 2014·European Journal of Clinical Pharmacology·R A PayneG A Abel
Aug 8, 2014·The Journal of Clinical Psychiatry·Richard S E KeefeManisha Madhoo
Apr 2, 2017·Journal of Affective Disorders·David V SheehanMatthieu Boucher

❮ Previous
Next ❯

Citations

Jun 1, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Marie-Hélène UwentsVincent Van Rompaey
May 27, 2021·The International Journal of Neuropsychopharmacology·Alexander BrunnauerGerd Laux

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Nihon rinsho. Japanese journal of clinical medicine
Taro Muramatsu
Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists
S MoritzMichael Krausz
© 2022 Meta ULC. All rights reserved