Droplet on demand system utilizing a computer controlled microvalve integrated into a stiff polymeric microfluidic device

Lab on a Chip
Krzysztof ChurskiPiotr Garstecki

Abstract

An integrated microvalve fabricated in a stiff polymeric (polycarbonate) device allows for formation of droplets and bubbles of arbitrary volumes and at arbitrary times of emission. Predesigned protocols of formation of sequences of volumes, intervals between the droplets and their chemical compositions can be practically and reproducibly realised and controlled from a personal computer. The design of the microvalve enables its utilization in chips made in a range of other materials, including plastics and glass and in devices operated both with positive and negative pressure providing a useful module for a range of applications of microfluidic droplet systems.

References

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Citations

May 27, 2011·Journal of Biological Engineering·Mandy Ly SinPak Kin Wong
Sep 20, 2011·Lab on a Chip·Jan GuzowskiPiotr Garstecki
May 15, 2013·Lab on a Chip·Sylwia MakulskaPiotr Garstecki
Aug 24, 2013·Lab on a Chip·Piotr M KorczykPiotr Garstecki
Sep 26, 2013·Lab on a Chip·Jan GuzowskiPiotr Garstecki
Nov 12, 2015·Lab on a Chip·Zhuang Zhi ChongNam-Trung Nguyen
Apr 25, 2015·Scientific Reports·Bárbara Schlicht, Michele Zagnoni
Oct 10, 2013·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Stig E FribergJoachim Koetz
Jun 29, 2013·Biosensors & Bioelectronics·Xia XiangZhike He
May 24, 2016·Lab on a Chip·Tomasz S KaminskiPiotr Garstecki
Nov 15, 2016·Lab on a Chip·Pingan Zhu, Liqiu Wang
Apr 17, 2013·Nature Reviews. Microbiology·Aimee K WesselMarvin Whiteley
Jul 14, 2012·Reports on Progress in Physics·Ralf SeemannStephan Herminghaus
Sep 26, 2012·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Robert HołystPiotr Garstecki
Apr 30, 2013·Journal of Physics D: Applied Physics·J K NunesH A Stone
Aug 1, 2015·Journal of Micromechanics and Microengineering : Structures, Devices, and Systems·Yi-Chun ChenR Michael van Dam
Jan 15, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Olgierd Cybulski, Piotr Garstecki
Jan 16, 2021·Analytical Chemistry·Yu ZhangMichele Zagnoni
May 14, 2010·Analytical Chemistry·Arun AroraAndreas Manz

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