Mar 21, 2016

Drosophila mutants that are motile but respond poorly to all stimuli tested

BioRxiv : the Preprint Server for Biology
Lar L Vang, Julius Adler


Adult Drosophila melanogaster fruit flies were placed into one end of a tube near to repellents (benzaldehyde and heat) and away from the other end containing attractants (light and a favored temperature). They escaped from the repellents and went to the attractants. Motile mutants that failed to do that were isolated. They did not respond to any external attractants tested or external repellents tested. In addition, they did not respond well to internal stimuli like hunger, thirst, and sleep. Some possibilities for explaining the deficiency: They may be considered defective in decision making that results from faulty interaction with the sensing mechanism, or, alternatively, the mutants may be defective in executive function. The mutants failed at both 34 degrees C and, in one case studied, at room temperature.

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Mentioned in this Paper

Cell Motility
Insect attractants
Mutant Proteins
Executive Function

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