Drosophila Mutants that Are Motile but Respond Poorly to All Stimuli Tested

BioRxiv : the Preprint Server for Biology
Lar L Vang, Julius Adler

Abstract

Adult Drosophila melanogaster fruit flies were placed into one end of a tube near to repellents (benzaldehyde and heat) and away from the other end containing attractants (light and a favored temperature). They escaped from the repellents and went to the attractants. Five motile mutants that failed to do that were isolated. They did not respond to any external attractants tested or external repellents tested. In addition, they did not respond well to internal sensory stimuli like hunger, thirst, and sleep. The mutants failed at both 34 degrees C and at room temperature. Some of the mutants have been mapped. It is proposed that the information from the different sensory receptors comes together at an intermediate, called inbetween (Inbet), that brings about a behavioral response.

Related Concepts

Benzaldehydes
Cell Motility
Drosophila
Sleep
Insect attractants
Biomedical Tube Device
Intermediate
Mutant
Receptor
Gene Mutant

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