PMID: 16510373Mar 3, 2006Paper

Drug delivery systems improve pharmaceutical profile and facilitate medication adherence

Advances in Therapy
Albert I WertheimerRichard A Levy

Abstract

Innovations in dosage forms and dose delivery systems across a wide range of medications offer substantial clinical advantages, including reduced dosing frequency and improved patient adherence; minimized fluctuation of drug concentrations and maintenance of blood levels within a desired range; localized drug delivery; and the potential for reduced adverse effects and increased safety. The advent of new large-molecule drugs for previously untreatable or only partially treatable diseases is stimulating the development of suitable delivery systems for these agents. Although advanced formulations may be more expensive than conventional dosage forms, they often have a more favorable pharmacologic profile and can be cost-effective. Inclusion of these dosage forms on drug formulary lists may help patients remain on therapy and reduce the economic and social burden of care.

References

Mar 2, 1994·JAMA : the Journal of the American Medical Association·J M McKenneyV M Chinchili
Sep 5, 1992·PharmacoEconomics·D A Sclar, T L Skaer
Feb 7, 2001·JAMA : the Journal of the American Medical Association·D E JoransonJ L Dahl
Sep 27, 2000·Hospital Practice·D Brookoff
Feb 15, 2001·Annals of Internal Medicine·W T CefaluUNKNOWN Inhaled Insulin Study Group
May 10, 2001·JAMA : the Journal of the American Medical Association·M C AudetUNKNOWN ORTHO EVRA/EVRA 004 Study Group
Dec 26, 2001·Journal of Clinical Epidemiology·J Dunbar-Jacob, M K Mortimer-Stephens
Jul 20, 2002·The Journal of Urology·Roger R DmochowskiUNKNOWN Transdermal Oxybutynin Study Group
Jul 23, 2002·JAMA : the Journal of the American Medical Association·Joshua S BennerJerry Avorn
Jul 23, 2002·JAMA : the Journal of the American Medical Association·Cynthia A JackeviciusJack V Tu
Nov 28, 2002·Clinical Pharmacokinetics·Yie W Chien, Senshang Lin
Nov 29, 2002·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·José A Rey
Mar 17, 2004·Current Opinion in Ophthalmology·Robert D Fechtner, Tony Realini
Oct 7, 2004·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Raymond C Love, Robert J Conley
Apr 20, 2005·PharmacoEconomics·Natalie C EdwardsRonald J Diamond
May 3, 2005·Obstetrics and Gynecology·Russell O Potts, Rogerio A Lobo
May 3, 2005·Nature Reviews. Drug Discovery·Howard Rosen, Thierry Abribat
Aug 11, 2005·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Yanni F YuJeonghoon Ahn

❮ Previous
Next ❯

Citations

Oct 20, 2006·Advances in Therapy·Richard Levy, Nancy Muller
Jan 1, 2010·Ecancermedicalscience·P KanavosZ Vlachopioti
Feb 18, 2012·Drug Development and Industrial Pharmacy·Geeta AggarwalS L Hari Kumar
May 10, 2011·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Mohammed TakiGary P Martin
Sep 15, 2011·Pharmaceutical Development and Technology·Geeta AggarwalS L Harikumar
Jul 8, 2017·CNS Spectrums·Andrew J Cutler, Gregory W Mattingly
Feb 9, 2019·Journal of Medical Economics·Jingping ZhaoJianwei Xuan
Apr 1, 2007·Expert Review of Pharmacoeconomics & Outcomes Research·Lizheng ShiKristina S Boye
Aug 8, 2020·Expert Review of Pharmacoeconomics & Outcomes Research·Ziyi Lin, Jianwei Xuan
Aug 28, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Stefania CometaElvira De Giglio

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.