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Drug development against smallpox: present and future

Antimicrobial Agents and Chemotherapy

Jan 15, 2020

Déborah Delaune, Frederic Iseni

Abstract

Forty years after the last endemic smallpox case, variola virus (VARV) is still considered a major threat to humans due to its possible use as a bioterrorism agent. For many years the risk of disease reemergence was thought to solely be through deliberate misuse of VARV strains kept in ...read more

Mentioned in this Paper

Pharmacologic Substance
Drug Development
Biological Warfare Agents
United States Food and Drug Administration
Smallpox Viruses
Research Study
Research
Antiviral Agents
World Health Organization
Poxviridae
3
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Drug development against smallpox: present and future

Antimicrobial Agents and Chemotherapy

Jan 15, 2020

Déborah Delaune, Frederic Iseni

PMID: 31932370

DOI: 10.1128/aac.01683-19

Abstract

Forty years after the last endemic smallpox case, variola virus (VARV) is still considered a major threat to humans due to its possible use as a bioterrorism agent. For many years the risk of disease reemergence was thought to solely be through deliberate misuse of VARV strains kept in ...read more

Mentioned in this Paper

Pharmacologic Substance
Drug Development
Biological Warfare Agents
United States Food and Drug Administration
Smallpox Viruses
Research Study
Research
Antiviral Agents
World Health Organization
Poxviridae
3

Similar Papers Found In These Feeds

Smallpox

Smallpox is caused by two variants of the variola virus, variola major and variola minor. It was eradicated in 1977, however it remains a concern owing to its potential use in bioterrorism. Discover the latest research on Smallpox here.

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

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Relevé épidémiologique Hebdomadaire

Smallpox eradication. WHO Advisory Committee on variola virus research

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Paper Details
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