PMID: 25739231Mar 6, 2015Paper

Drug discrimination by near infrared spectroscopy based on summation wavelet extreme learning machine

Guang pu xue yu guang pu fen xi = Guang pu
Zhenbing LiuXue-Bo Zhang

Abstract

As an effective technique to identify counterfeit drugs, Near Infrared Spectroscopy has been successfully used in the drug management of grass-roots units, with classifier modeling of Pattern Recognition. Due to a major disadvantage of the characteristic overlap and complexity, the wide bandwidth and the weak absorption of the Spectroscopy signals, it seems difficult to give a satisfactory solutions for the modeling problem. To address those problems, in the present paper, a summation wavelet extreme learning machine algorithm (SWELM(CS)) combined with Cuckoo research was adopted for drug discrimination by NIRS. Specifically, Extreme Learning Machine (ELM) was selected as the classifier model because of its properties of fast learning and insensitivity, to improve the accuracy and generalization performances of the classifier model; An inverse hyperbolic sine and a Morlet-wavelet are used as dual activation functions to improve convergence speed, and a combination of activation functions makes the network more adequate to deal with dynamic systems; Due to ELM' s weights and hidden layer threshold generated randomly, it leads to network instability, so Cuckoo Search was adapted to optimize model parameters; SWELM(CS) improves st...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Neural Networks : the Official Journal of the International Neural Network Society
Andrés Bueno-CrespoJosé-Luis Sancho-Gómez
International Journal of Neural Systems
Akio Yamazaki, Teresa B Ludermir
© 2022 Meta ULC. All rights reserved