Drug-eluting stents versus bare metal stents for narrowing in saphenous vein grafts

The American Journal of Cardiology
Teruo OkabeRon Waksman

Abstract

Conflicting data exist regarding an advantage of drug-eluting stents (DES) over bare metal stents (BMS) in catheter-based treatment of saphenous vein graft (SVG) stenoses. This study was undertaken to compare the efficacy of these modalities in that lesion subset. The DES group consisted of 138 cases with 183 lesions (sirolimus-eluting stents, n = 117; paclitaxel-eluting stents, n = 66) and the BMS group consisted of 344 cases with 478 lesions that were followed to 1 year. We examined a composite end point that comprised death, Q-wave myocardial infarction, and target lesion revascularization. More BMS were deployed per patient (p <0.001) and the diameters of BMS deployed was significantly greater (p <0.001). Peak postprocedure values of creatine kinase-MB (p = 0.003) and troponin I (p = 0.05) were higher in BMS. At 1 year there was no significant superiority of DES over BMS with regard to hard end points (death and Q-wave myocardial infarction). In conclusion, this study indicates that both DES and BMS for SVG disease provide acceptably safe and efficacious results, but unlike the case in native coronary arteries, DES use does not reduce the frequency of the need for repeat revascularization.

References

Jul 1, 1996·Journal of the American College of Cardiology·P P de JaegereP W Serruys
Feb 17, 2000·Journal of the American College of Cardiology·B BhargavaM B Leon
Jun 7, 2002·The New England Journal of Medicine·Marie-Claude MoriceUNKNOWN RAVEL Study Group. Randomized Study with the Sirolimus-Coated Bx Velocity Balloon-Expandable Stent in the Treatment of Patie
Oct 3, 2003·The New England Journal of Medicine·Jeffrey W MosesUNKNOWN SIRIUS Investigators
Aug 2, 2005·The American Journal of Cardiology·Keiichi TsuchidaPatrick W Serruys
Dec 27, 2005·The American Journal of Cardiology·William W ChuRon Waksman

❮ Previous
Next ❯

Citations

Dec 22, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Alessandro LupiAntonio Buffon
Apr 18, 2009·Future Cardiology·Mehmood ButtGregory Y H Lip
Oct 5, 2010·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Luca TestaFrancesco Bedogni
Feb 10, 2010·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Emmanouil S BrilakisSubhash Banerjee
Jun 15, 2010·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Angel Sanchez-RecaldeJose L Lopez-Sendon
Feb 19, 2011·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Satheesh NairMamas A Mamas
Feb 19, 2014·Expert Opinion on Drug Delivery·Ricardo O EscárcegaRon Waksman
Dec 14, 2011·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Sílvio LealUNKNOWN ACROSS Registry Investigators
Apr 13, 2010·The American Journal of Cardiology·Michael S LeeEhtisham Mahmud
Mar 21, 2012·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Paul H TolericoUNKNOWN EVENT Investigators
Feb 18, 2011·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Abdul HakeemImran Arif
Mar 17, 2012·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Vincenzo PasceriPasquale Lisanti
Feb 2, 2011·Journal of Interventional Cardiology·Mamas A MamasFarzin Fath-Ordoubadi
Dec 15, 2012·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Luiz F YbarraExpedito E Ribeiro
Dec 7, 2013·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Mikkel HougaardLisette Okkels Jensen
Sep 30, 2009·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nilesh J GoswamiGregory J Mishkel
Mar 11, 2009·Journal of Biomedical Materials Research. Part a·Feng ChaiHartmut F Hildebrand
Jun 3, 2010·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Shahar LaviVladimír Dzavík
Jan 5, 2011·The American Journal of Cardiology·Bimmer E ClaessenGeorge D Dangas
Sep 29, 2009·American Heart Journal·Mehdi H ShishehborSamir R Kapadia
May 30, 2009·Journal of the American College of Cardiology·Simon R DixonWilliam W O'Neill
Jan 15, 2011·JACC. Cardiovascular Interventions·Matthew E WiisanenKhaled M Ziada
Feb 16, 2010·American Heart Journal·Dominique JoyalMark J Eisenberg
Nov 26, 2010·Circulation. Cardiovascular Interventions·Jean-Michel ParadisStéphane Rinfret

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Related Papers

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
Ravi K RamanaBruce E Lewis
Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
Giuseppe GioiaWilliam Matthai
EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Abid AssaliRan Kornowski
Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
Michael S LeeRaj R Makkar
© 2022 Meta ULC. All rights reserved