Drug-induced anaphylaxis in China: a 10 year retrospective analysis of the Beijing Pharmacovigilance Database

International Journal of Clinical Pharmacy
Ying ZhaoTiansheng Wang

Abstract

Background Few studies on the causes of drug-induced anaphylaxis (DIA) in the hospital setting are available. Objective We aimed to use the Beijing Pharmacovigilance Database (BPD) to identify the causes of DIA in Beijing, China. Setting Anaphylactic case reports from the BPD provided by the Beijing Center for Adverse Drug Reaction Monitoring. Method DIA cases collected by the BPD from January 2004 to December 2014 were adjudicated. Cases were analyzed for demographics, causative drugs and route of administration, and clinical signs and outcomes. Main outcome measure Drugs implicated in DIAs were identified and the signs and symptoms of the DIA cases were analyzed. Results A total of 1189 DIA cases were analyzed. The mean age was 47.6 years, and 732 (61.6%) were aged from 18 to 59 years. A total of 627 patients (52.7%) were females. There was a predominance of cardiovascular (83.8%) followed by respiratory (55.4%), central nervous (50.1%), mucocutaneous (47.4%), and gastrointestinal symptoms (31.3%). A total of 249 different drugs were involved. DIAs were mainly caused by antibiotics (39.3%), traditional Chinese medicines (TCM) (11.9%), radiocontrast agents (11.9%), and antineoplastic agents (10.3%). Cephalosporins accounted fo...Continue Reading

References

Jul 31, 2001·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·A CianferoniA Vierucci
Nov 3, 2001·The Journal of Allergy and Clinical Immunology·A F BrownK Chu
Aug 10, 2010·The Journal of Allergy and Clinical Immunology·Phillip LiebermanDana Wallace
Aug 3, 2011·Clinics·Dirceu SoleUNKNOWN Latin American Anaphylaxis Working Group
Aug 24, 2012·European Journal of Clinical Pharmacology·Inês Ribeiro-VazEva Rebelo Gomes
Oct 20, 2012·World Journal of Gastroenterology : WJG·Jui-Ho WangChao-Wen Hsu
Oct 15, 2013·Allergy·S S PanesarUNKNOWN EAACI Food Allergy and Anaphylaxis Group
Jun 10, 2014·Allergy·A MuraroUNKNOWN EAACI Food Allergy and Anaphylaxis Guidelines Group
Oct 5, 2014·The Journal of Allergy and Clinical Immunology·Elina JerschowAileen P McGinn
Oct 7, 2014·JAMA Internal Medicine·Jin WangYonghong Xiao
Oct 31, 2014·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Nonna V KolomeyevskayaPeter J Frederick
Jan 2, 2015·Allergy, Asthma & Immunology Research·Young-Min YeUNKNOWN KAAACI Work Group on Urticaria/Angioedema/Anaphylaxis
Nov 4, 2015·The World Allergy Organization Journal·F Estelle R SimonsAziz Sheikh
Jan 26, 2016·CA: a Cancer Journal for Clinicians·Wanqing ChenJie He
Sep 21, 2016·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S R KimJ W Park
May 16, 2017·International Archives of Allergy and Immunology·Tiansheng WangSuodi Zhai

❮ Previous
Next ❯

Citations

Jul 28, 2018·International Journal of Clinical Pharmacy·Ying ZhaoShusen Sun
Jun 21, 2019·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Elizabeth H ThamUNKNOWN APAPARI Anaphylaxis Study Group
Nov 28, 2018·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Khac-Dung NguyenHaleh Bagheri
Sep 30, 2020·The Journal of Allergy and Clinical Immunology. in Practice·Roger J YuCosby A Stone
Feb 11, 2021·Journal of Clinical Pharmacy and Therapeutics·Khac-Dung NguyenHaleh Bagheri
Feb 17, 2021·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Hyo-In RhyouYoung-Min Ye
Feb 20, 2021·Clinical Reviews in Allergy & Immunology·Yue ShiThomas A E Platts-Mills
Jul 13, 2021·Frontiers in Genetics·Hoang Kim Tu TrinhHae-Sim Park

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Beta-lactamase Inhibitors

Beta-lactamase inhibitors are a class of antibiotics that inhibit beta-lactamases, a family of enzymes involved in bacterial resistance to beta-lactam antibiotics. Here is the latest research.

Beta-lactamase Inhibitors (ASM)

Beta-lactamase inhibitors are a class of antibiotics that inhibit beta-lactamases, a family of enzymes involved in bacterial resistance to beta-lactam antibiotics. Here is the latest research.

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.