Drug-induced metabolic disorders and parenteral nutrition in the intensive care unit: a pharmaceutical and metabolic perspective

DICP : the Annals of Pharmacotherapy
D F Driscoll

Abstract

Since its inception, the field of parenteral nutrition has continued to evolve requiring the expertise of several health care disciplines. This feature has made nutrition support unique among clinical subspecialties. As a member of this team, the pharmacist plays a critical role in the provision of sterile admixtures, compatible nutritional formulations, and cost-effective, therapeutically equivalent strategies. The pharmacist has become more involved in the clinical care of the patient, with particular emphasis on the development of drug-induced metabolic disorders. The multitude of drugs prescribed to hospitalized patients increases the potential for serious metabolic disturbances. This is especially true in the critical care setting where sudden changes in metabolism (e.g., acid-base homeostasis, fluid and electrolyte balance) may result in profoundly negative effects. The critical care setting also represents the most sensitive period of hospitalization where even subtle changes in metabolic homeostasis may assume major clinical significance. Early recognition of offending agents and the institution of appropriate intervention may avert serious iatrogenic diseases. The nutrition support team is in a unique position to addre...Continue Reading

References

Dec 1, 1978·Annals of Internal Medicine·R D LentzC M Kjellstrand
Aug 1, 1979·Archives of Surgery·R GazituaG L Blackburn
Jul 1, 1975·Archives of Surgery·A H HarkenF D Moore
May 1, 1975·Archives of Neurology·R J Porter, R B Layzer
Apr 1, 1978·Southern Medical Journal·W D BlackJ Roman
Mar 11, 1977·Science·G WildingE S Vesell
Oct 27, 1977·The New England Journal of Medicine·L R O'ConnorJ E Bethune
Feb 5, 1976·The New England Journal of Medicine·J Koch-Weser, E M Sellers
Apr 1, 1975·The Journal of Clinical Investigation·R A DeFronzoP J Davis
Sep 1, 1987·The American Journal of Cardiology·J D CohenK A Daniels
Nov 1, 1985·Medicine·S P PonceJ T Harrington
Jul 1, 1986·Kidney International·J T HarringtonN E Madias
Sep 1, 1986·JPEN. Journal of Parenteral and Enteral Nutrition·M GilbertM F Elmore
Nov 1, 1986·JPEN. Journal of Parenteral and Enteral Nutrition·R BrownR Sigman
Jul 1, 1987·Drug Intelligence & Clinical Pharmacy·C E RoweJ T Martinoff
Jul 1, 1988·Drug Intelligence & Clinical Pharmacy·R J Baptista, F P Mitrano
Mar 1, 1986·Transplantation·T A GrayP McMaster
Aug 1, 1987·Brain : a Journal of Neurology·B P Illowsky, R Laureno
Nov 1, 1987·Annals of Internal Medicine·R H Sterns
Sep 1, 1986·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M Lam, D J Adelstein
Aug 15, 1985·The New England Journal of Medicine·M AubierR Pariente
Feb 1, 1985·The Surgical Clinics of North America·R L JenkinsR L Rossi
Nov 15, 1985·American Journal of Obstetrics and Gynecology·A F StewartP E Schwartz
Jun 20, 1974·The New England Journal of Medicine·M A Lichtman
Jun 1, 1971·The Journal of Clinical Investigation·D V KimbergR T Graudusius
Mar 7, 1974·The New England Journal of Medicine·J F Morrissey, R F Barreras
May 3, 1973·The New England Journal of Medicine·J S FordtranC T Richardson
Sep 19, 1968·The New England Journal of Medicine·W B SchwartzJ P Kassirer
Jan 1, 1969·The American Journal of Medicine·J B Douglas, J K Healy
Aug 18, 1972·Science·C S AnastT W Burns
Mar 1, 1970·The Journal of Clinical Investigation·P R Steinmetz, L R Lawson
Jan 18, 1968·The New England Journal of Medicine·D K McCurdyJ R Elkinton
Feb 22, 1968·The New England Journal of Medicine·M LotzF C Bartter
Oct 1, 1966·The Journal of Clinical Investigation·E J LennonJ R Litzow
Jan 1, 1984·World Review of Nutrition and Dietetics·A Gayte-Sorbier, C B Airaudo
Jul 1, 1983·The Medical Clinics of North America·M G CoganF C Rector
Aug 1, 1982·Critical Care Medicine·M M EcheniqueG L Blackburn
Jul 1, 1982·JPEN. Journal of Parenteral and Enteral Nutrition·M M MeguidD C Nabseth
Sep 1, 1981·The American Journal of Medicine·H J Adrogué, N E Madias
Jan 1, 1982·Annual Review of Medicine·R A DeFronzoD Smith
Mar 1, 1981·The Medical Clinics of North America·M Cox

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Citations

Oct 24, 2006·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·David F DriscollJörg Nehne

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