PMID: 79927Sep 9, 1978Paper

Drug-induced myopathies in man

Lancet
R J Lane, F L Mastaglia

Abstract

Drug-induced diseases constitute up to 5% of hospital admissions,a figure which almost certainly understates the total morbidity due to drugs1. Sever drug-induced myopathies are uncommon, but milder forms may be more prevalent than is generally appreciated, since skeletal muscle constitutes some 45% of total body-weight and has a major metabolic role in addition to its mechanical function2. Knowledge of possible effects of drugs on the neuromuscular system is of increasing importance both because the range of therapeutic agents continues to expand and because the resulting syndromes, through usually reversible at the outset, may progress and lead to grave consequences if the drug responsible is not stopped. Drug-induced neuropathies3 will not be considered here, but it will be appreciated that muscle weakness may also be feature of such disorders and that some drugs may cause both a neuropathy and a myopathy. The features of the main drug-induced syndromes are summarised in the table. To these one could justifiably add the unwanted effects of srugs given for the treatment of central-nervous-system or neuromuscular disorders per se-e.g., the cholinergic block which may be produced by anticholinesterases alone or with corticoster...Continue Reading

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Citations

Jan 1, 1980·Virchows Archiv. A, Pathological Anatomy and Histology·H J Manz
Jan 1, 1990·Intensive Care Medicine·D AnnaneP Auzepy
Mar 8, 2008·Pituitary·Eva Fernandez-RodriguezMark S Cooper
Dec 9, 1991·Neuroscience Letters·F BaldisseraF Dworzak
Jan 1, 1981·Progress in Neuro-psychopharmacology·C A NaranjoE M Sellers
Nov 1, 1986·Disease-a-month : DM·S M Campbell, R M Bennett
Sep 1, 1990·Baillière's Clinical Endocrinology and Metabolism·J B Harris, P G Blain
Sep 23, 1982·The New England Journal of Medicine·D Sinclair, C Phillips
Jan 5, 2002·The American Journal of Geriatric Cardiology·Domenic A Sica, Todd W B Gehr
Oct 1, 1993·Neuropathology and Applied Neurobiology·R J LaneD F Woodrow
Dec 1, 1990·Australian and New Zealand Journal of Medicine·K H MakY S Lee
Jul 12, 1980·British Medical Journal·C K BiswasP J Tilley
Sep 10, 1983·British Medical Journal·P Kendall-Taylor, D M Turnbull
Aug 16, 1986·British Medical Journal·E HodakM Sandbank
Sep 17, 1988·BMJ : British Medical Journal·A J Carmichael, A M Martin
Jun 1, 1982·Journal of Neurology, Neurosurgery, and Psychiatry·K R MillsR H Edwards
Feb 1, 1985·Journal of Neurology, Neurosurgery, and Psychiatry·L H Kortbeek, M W van Beek
Mar 1, 1996·Journal of Neurology, Neurosurgery, and Psychiatry·F L Mastaglia, N G Laing
May 1, 1993·Postgraduate Medical Journal·B D Prendergast, C F George
Jan 1, 1983·Scandinavian Journal of Infectious Diseases·H A KesslerS Levin
Jan 1, 1984·Critical Reviews in Clinical Laboratory Sciences·J A Lott, P W Landesman
Mar 11, 2005·Neurologic Clinics·Ronan J Walsh, Anthony A Amato
Oct 1, 1989·Australian and New Zealand Journal of Medicine·P D Clouston, P E Donnelly
Jun 15, 2007·Toxicologic Pathology·Miyoko OkadaShiro Takagi
Oct 1, 1986·Journal of Child Neurology·C K Jablecki
Feb 11, 2012·Journal of Korean Medical Science·Su-Jin SeokSae-Yong Hong
Sep 17, 1988·BMJ : British Medical Journal·M E Nelson, A Z Andrzejowski
Sep 17, 1988·BMJ : British Medical Journal·A SchattnerZ Bentwich
Mar 1, 1981·Arquivos de neuro-psiquiatria·L C WerneckJ C Lozovey
Aug 9, 2003·Expert Opinion on Drug Safety·Terry A Jacobson
Jan 1, 1980·British Journal of Pharmacology·A H BretagA G Moskwa
Apr 24, 2015·Current Rheumatology Reports·Emma HarrisSarah Louise Mackie
Jan 2, 2021·Current Problems in Cardiology·Rahul GuptaAaqib H Malik
Jan 12, 2021·Curēus·Vishwajit HegdeMichael Anstead
Dec 12, 1981·The Medical Journal of Australia·M Kennedy
Jan 1, 2003·Rheumatic Diseases Clinics of North America·Ann M Reed, Steven R Ytterberg
Oct 1, 1989·Annals of Emergency Medicine·S C CurryD Connor

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