Drug-induced optic neuropathy in a case of extensively drug-resistant pulmonary tuberculosis

Journal of Basic and Clinical Physiology and Pharmacology
Proteesh RanaJamshed Ahmad

Abstract

We report a 26-year-old male patient diagnosed with extensively drug-resistant pulmonary tuberculosis presenting with reversible bilateral toxic optic neuropathy induced by the use of linezolid along with high-dose isoniazid. The case emphasizes the importance of recognizing toxic optic neuritis in patients on antitubercular therapy. Prompt recognition and treatment of such adverse drug reactions will reduce the associated morbidity.

References

Aug 1, 1981·Clinical Pharmacology and Therapeutics·C A NaranjoD J Greenblatt
Nov 22, 2005·The British Journal of Ophthalmology·K Kulkarni, L V Del Priore
Aug 16, 2006·Expert Opinion on Drug Safety·Frederick W FraunfelderTerry Wood
Dec 21, 2006·The British Journal of Ophthalmology·M JavaheriA A Sadun
Jul 14, 2010·Indian Pediatrics·H S KulkarniY Gabhale
Oct 12, 2010·Indian Journal of Pharmacology·Rahul MagazineVeena Nayak
Feb 26, 2011·Indian Journal of Ophthalmology·Pradeep Sharma, Reena Sharma

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