Drug interaction screening in SWOG clinical trials

American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Daniel L HertzSiu Fun Wong

Abstract

The frequency and process for drug interaction (DI) screening at sites enrolling patients into SWOG clinical trials were studied. Survey invitations were e-mailed to 180 SWOG head clinical research associates to determine the frequency of and personnel involved in DI assessment in subjects who were screened for and enrolled in clinical trials at their sites. Descriptive statistics were performed to evaluate the data. A total of 83 surveys recorded a response to at least 1 question, yielding an overall response rate of 46.1%. At least 72 completed surveys were submitted, for a completion rate of 40.0%. The majority of sites (51%) reported that DI screening only occurred during eligibility assessment when a DI was included in the protocol exclusion criteria. The pharmacist was "always" involved in DI screening during eligibility assessment at 17% of sites. Clinical research coordinators (56%) and research nurses (45%) were the predominant personnel who performed DI screening to assess eligibility for trial enrollment. A subset of sites (3-6%) reported not having access to a pharmacist. Fewer than 10% of sites reported that they "always" use drug information services, websites, resources, or literature searches, though many tools ...Continue Reading

References

Dec 15, 2006·British Journal of Clinical Pharmacology·Agnes I Vitry
Mar 7, 2008·American Journal of Pharmaceutical Education·Jolaine Reierson DraugalisCecilia M Plaza
May 17, 2008·American Journal of Pharmaceutical Education·Jack E Fincham
May 20, 2008·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Yu KoRaymond L Woosley
Dec 10, 2008·Research in Social & Administrative Pharmacy : RSAP·Yu KoRaymond L Woosley
Feb 24, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·R W F van LeeuwenJ G Hugtenburg
Jul 7, 2011·Pharmacoepidemiology and Drug Safety·Alexandre ChanUNKNOWN Onco-Informatics (onco-informatics.com) Group
Nov 4, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·B YouE Chen
Mar 31, 2012·Clinical Journal of Oncology Nursing·Mikaël DaoupharsRemi Varin
Mar 4, 2014·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Justin P TurnerJ Simon Bell
May 2, 2014·Journal of Pain and Symptom Management·Aleksandra Kotlinska-LemieszekPål Klepstad
May 14, 2014·Journal of Geriatric Oncology·Mihaela A PopaLodovico Balducci
May 17, 2014·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Siu-Fun WongElvin Hernandez
Jan 4, 2015·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Richard T ScheifeDaniel C Malone
Jan 30, 2015·Annals of Oncology : Official Journal of the European Society for Medical Oncology·R W F van LeeuwenT van Gelder
May 20, 2015·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Kari B WisinskiJill M Kolesar
Nov 7, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Katharina A KiernerHerbert H Watzke
Mar 10, 2016·Journal of the National Comprehensive Cancer Network : JNCCN·Siu-Fun WongTimothy Chen
Aug 9, 2016·Journal of Geriatric Oncology·Manvi SharmaHolly M Holmes
Jan 1, 2015·Asia-Pacific Journal of Oncology Nursing·Azize KarahanAysel Abbasoglu
Feb 24, 2017·BMC Medical Informatics and Decision Making·Katrina M RomagnoliHarry Hochheiser
Apr 9, 2017·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Kayla E McGahey, Glen J Weiss

❮ Previous
Next ❯

Citations

May 12, 2018·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Susan Goodin
Mar 28, 2021·BMC Cancer·Lauren A MarcathDaniel L Hertz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Anand KhandoobhaiNiesha Griffith
International Journal of Medical Informatics
Marine L AnderssonBirgit Eiermann
© 2022 Meta ULC. All rights reserved