Drug-nutrient interactions

Nutrition Reviews
J A Thomas

Abstract

Nutrition status plays a significant role in a drug's pharmacodynamics. Some disease states and other special conditions affect nutrient status and a drug's therapeutic efficacy. Many classes of drugs, including antimicrobials, hypoglycemics, and hypocholesterolemic agents, can be affected by the presence of food, with the geriatric patient particularly at risk. While a drug's pharmacokinetic profile can usually be predicted, it can be modified by nutrients and by certain pathophysiologic conditions, including aging, hepatic dysfunction, and micronutrients.

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Citations

Jun 1, 2010·The Proceedings of the Nutrition Society·Pamela Mason
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Sep 16, 2003·Journal of Clinical Pharmacology·Thorir D BjornssonCaroline Loew
Jan 15, 2005·Pharmacoepidemiology and Drug Safety·Joseph R SharkeySuojin Wang

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