PMID: 6399066Dec 1, 1984Paper

"Drug-resistant proportion test" for M. leprae to quantify the proportion of drug-resistant M. leprae in a sample using the mouse foot pad

International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association
J G AlmeidaC J Chacko

Abstract

The mouse foot pad test has not previously been used quantitatively to discriminate between samples of Mycobacterium leprae with differing proportions of drug-resistant M. leprae. The "drug-resistant proportion test" is a simple modification of the routine mouse foot pad test. It is demonstrated to distinguish between samples of M. leprae with a tenfold difference in the proportion of dapsone-resistant M. leprae.

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