Drug therapy for patients with eating disorders

Current Drug Targets. CNS and Neurological Disorders
J E MitchellJames L Roerig

Abstract

The purpose of this article is to review the psychopharmacology treatment literature for patients with eating disorders including bulimia nervosa, anorexia nervosa and binge eating disorder. The best-developed treatment literature concerns bulimia nervosa, which has been studied now in several dozen pharmacological treatment studies. The agents most commonly used are the antidepressants, with particular focus on the selective serotonin reuptake inhibitors including fluoxetine hydrochloride. These agents clearly impact significantly on the frequency of abnormal eating behaviors such as binge eating and purging. However, subjects treated with these drugs rarely achieve remission. Pharmacotherapy of anorexia nervosa has also traditionally focused on the use of antidepressants and there is some evidence that the use of SSRIs may help in preventing relapse in weight restored patients. Recently interest has developed in the use of atypical neuroleptics to help with the obsessionality and resistance to treatment frequently seen in low weight patients, the most commonly employed agent being olanzapine. Pharmacotherapy of binge-eating disorder is now being intensively investigated. In general medication alone seems inferior to psychothe...Continue Reading

Citations

Nov 25, 2004·Best Practice & Research. Clinical Gastroenterology·Donald A WilliamsonTiffany Stewart
Feb 11, 2005·The Australian and New Zealand Journal of Psychiatry·Peter BosanacPeter Beumont
Dec 16, 2005·Pharmacogenomics·Kathryn J StrandMeena Augustus
Mar 15, 2005·Journal of Endocrinological Investigation·G Abbate DagaS Fassino
Nov 2, 2013·BMC Psychiatry·Marloes S OudijnDamiaan Denys
Apr 26, 2006·Expert Opinion on Emerging Drugs·Kristine J SteffenSaritha Uppala
Apr 22, 2008·Pharmacology, Biochemistry, and Behavior·G D GamaroC Dalmaz
Apr 6, 2007·La Presse médicale·Daniel RigaudJean-Marcel Brun
Jan 15, 2008·Physiology & Behavior·Patricia L FarisBoyd K Hartman
Oct 16, 2007·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Liana FattoreWalter Fratta
Nov 16, 2007·European Eating Disorders Review : the Journal of the Eating Disorders Association·Claudia Mehler-WexUlrike M E Schulze
Oct 19, 2005·The International Journal of Eating Disorders·Cerstin NickelMarius K Nickel
Mar 31, 2011·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Yushi UtumiHeii Arai
Sep 17, 2014·Acta Psychiatrica Scandinavica·Y von Hausswolff-JuhlinM Larsson
Feb 24, 2005·Journal of Psychiatric Research·K HoltkampB Herpertz-Dahlmann
Dec 28, 2006·The Annals of Pharmacotherapy·Kaelen C Dunican, Dana DelDotto
Jun 17, 2006·Eating Disorders·Maria J FrischDavid B Herzog
Oct 5, 2010·Pediatrics in Review·Cora Collette Breuner
Aug 16, 2005·Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie·Claudia Mehler-WexAndreas Warnke
Oct 13, 2004·The International Journal of Eating Disorders·Rachel J PlacidiMary M Boggiano
May 24, 2007·International Clinical Psychopharmacology·Francesca BrambillaPalmiero Monteleone
May 23, 2009·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Angelo Antonini, Roberto Cilia

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