Drug therapy for treating post-dural puncture headache.

The Cochrane Database of Systematic Reviews
Xavier Basurto OnaXavier Bonfill Cosp

Abstract

This is an updated version of the original Cochrane review published in Issue 8, 2011, on 'Drug therapy for treating post-dural puncture headache'.Post-dural puncture headache (PDPH) is the most common complication of lumbar puncture, an invasive procedure frequently performed in the emergency room. Numerous pharmaceutical drugs have been proposed to treat PDPH but there are still some uncertainties about their clinical effectiveness. To assess the effectiveness and safety of drugs for treating PDPH in adults and children. The searches included the Cochrane Central Register of Controlled Trials (CENTRAL 2014, Issue 6), MEDLINE and MEDLINE in Process (from 1950 to 29 July 2014), EMBASE (from 1980 to 29 July 2014) and CINAHL (from 1982 to July 2014). There were no language restrictions. We considered randomised controlled trials (RCTs) assessing the effectiveness of any pharmacological drug used for treating PDPH. Outcome measures considered for this review were: PDPH persistence of any severity at follow-up (primary outcome), daily activity limited by headache, conservative supplementary therapeutic option offered, epidural blood patch performed, change in pain severity scores, improvements in pain severity scores, number of day...Continue Reading

Associated Clinical Trials

May 26, 2020·Naglaa Fathy Abdelhaleem Abdelhaleem

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Citations

Mar 8, 2016·The Cochrane Database of Systematic Reviews·Ingrid Arevalo-RodriguezXavier Bonfill Cosp
Mar 24, 2016·Neurocritical Care·Laxmi P DhakalWilliam D Freeman
Jan 10, 2019·Minerva anestesiologica·Bigna S BuddebergThierry Girard
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Dec 17, 2020·Neurological Research and Practice·Aleksander Fjeld HaugstvedtHanne Christensen
May 29, 2021·Der Nervenarzt·Katharina Kamm, Stefanie Förderreuther
Mar 17, 2021·Der Schmerz·Katharina Kamm, Stefanie Förderreuther
Mar 9, 2020·Ophthalmic Research·Christoph LeisserMartin Kronschläger

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