Drug-therapy networks and the prediction of novel drug targets.

Journal of Biology
Zoltan SpiroPeter Csermely

Abstract

A recent study in BMC Pharmacology presents a network of drugs and the therapies in which they are used. Network approaches open new ways of predicting novel drug targets and overcoming the cellular robustness that can prevent drugs from working.

References

Dec 26, 2001·Nucleic Acids Research·X ChenY Z Chen
Jun 12, 2003·Proceedings of the National Academy of Sciences of the United States of America·Alexis A BorisyCurtis T Keith
Jan 22, 2004·Nature Reviews. Genetics·Albert-László Barabási, Zoltán N Oltvai
Nov 3, 2004·Nature Reviews. Genetics·Hiroaki Kitano
Dec 21, 2004·Nucleic Acids Research·Ada HamoshVictor A McKusick
Apr 6, 2005·Trends in Pharmacological Sciences·Péter CsermelySándor Pongor
Aug 6, 2005·The Journal of Biological Chemistry·Stephen Fitter, Robert James
Jul 15, 2006·Nature Biotechnology·Gaia V PaoliniAndrew L Hopkins
Feb 6, 2007·PLoS Computational Biology·Stefano CilibertiAndreas Wagner
Feb 24, 2007·Nature Reviews. Drug Discovery·Hiroaki Kitano
May 16, 2007·Proceedings of the National Academy of Sciences of the United States of America·Kwang-Il GohAlbert-László Barabási
May 23, 2007·The Mount Sinai Journal of Medicine, New York·Avi Ma'ayanRavi Iyengar
Sep 22, 2007·BMC Bioinformatics·Qingliang Li, Luhua Lai
Oct 9, 2007·Nature Biotechnology·Muhammed A YildirimMarc Vidal
Nov 16, 2007·Proteins·Keunwan Park, Dongsup Kim
Dec 1, 2007·Nucleic Acids Research·David S WishartMurtaza Hassanali
Feb 20, 2008·BMC Bioinformatics·Zhenting GaoHualiang Jiang
Mar 6, 2008·BMC Pharmacology·Jose C Nacher, Jean-Marc Schwartz
Mar 11, 2008·Proceedings of the National Academy of Sciences of the United States of America·Igor FeldmanDennis Vitkup
Mar 22, 2008·Proceedings of the National Academy of Sciences of the United States of America·Pak Kin WongChih-Ming Ho
Jul 16, 2008·Science·Monica CampillosPeer Bork

❮ Previous
Next ❯

Citations

Dec 30, 2009·Briefings in Bioinformatics·Jing ZhaoWeidong Zhang
May 30, 2013·Nucleic Acids Research·Zhenjun HuCharles Delisi
Apr 9, 2009·BMC Chemical Biology·Jean-Marc Schwartz, Jose C Nacher
Nov 6, 2013·Biology Direct·Sandeep Kumar DhandaGajendra P S Raghava
Jan 22, 2013·BMC Systems Biology·Dávid FazekasTamás Korcsmáros
Sep 26, 2009·PLoS Computational Biology·Jiguang WangXiang-Sun Zhang
Jan 25, 2013·Viruses·Magali E Droniou-Bonzom, Paula M Cannon
May 11, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Jiangyong GuXiaojie Xu
Nov 13, 2012·Expert Opinion on Drug Discovery·Nagasuma Chandra, Jyothi Padiadpu
Sep 1, 2012·Drug Discovery Today·Zhichao LiuWeida Tong
May 15, 2012·Parkinsonism & Related Disorders·André X C N ValentePaulo J Oliveira
Aug 17, 2010·Current Opinion in Biotechnology·Antonio del SolDavid Galas
Oct 20, 2009·Trends in Biochemical Sciences·Chung-Jung TsaiRuth Nussinov
Apr 11, 2013·Scientific Reports·Jose C Nacher, Tatsuya Akutsu
Nov 26, 2014·Current Protocols in Bioinformatics·Zhenjun Hu
Oct 22, 2008·Nature Chemical Biology·Andrew L Hopkins
Jul 27, 2011·Molecular BioSystems·Andreas BernthalerRainer Oberbauer
Aug 8, 2014·Molecular BioSystems·Jaymin J KathiriyaVrushank Davé
Feb 9, 2011·Médecine sciences : M/S·Sharon Harel, Sarah Jenna
May 6, 2017·Briefings in Bioinformatics·Zhen ShengZhiwei Cao
Feb 22, 2021·Interdisciplinary Sciences, Computational Life Sciences·Xin ChenJiawei Luo
Aug 12, 2009·Journal of Chemical Information and Modeling·Harsha GurulingappaJuliane Fluck
Jun 9, 2021·Nature Communications·Chen ChenWei Min
May 19, 2011·Science Signaling·Illés J FarkasPeter Csermely

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

BMC Pharmacology
Jose C Nacher, Jean-Marc Schwartz
Nature Biotechnology
Muhammed A YildirimMarc Vidal
Proceedings of the National Academy of Sciences of the United States of America
Kwang-Il GohAlbert-László Barabási
Expert Opinion on Drug Discovery
Tamás KorcsmárosPeter Csermely
© 2022 Meta ULC. All rights reserved