Aug 1, 1977

Drug treatment of malignant hyperpyrexia

Anaesthesia and Intensive Care
K L Austin, M A Denborough

Abstract

Of the various drugs currently suggested for the treatment of malignant hyperpyrexia, dantrolene sodium was the most effective in reversing and inhibiting drug induced contractures in vitro, both in normal muscle and in muscle from patients who are susceptible to malignant hyperpyrexia. It is suggested that dantrolene sodium is the drug of choice for lowering the raised myoplasmic calcium concentrations in malignant hyperpyrexia.

  • References6
  • Citations16

Mentioned in this Paper

Dantrolene Sodium
Calcium
Hydantoins
Dantrium
Quick-Pep
Pharmacologic Substance
Muscle
Pharmacotherapy
Inotropism
Malignant Hyperpyrexia due to Anesthesia

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