PMID: 8607630Mar 1, 1996Paper

Drugs associated with bullous pemphigoid. A case-control study

Archives of Dermatology
S Bastuji-GarinJ C Roujeau

Abstract

Bullous pemphigoid is the most frequent autoimmune blistering disease. It occurs in the elderly. The cause of this disease is unknown, but cases of bullous pemphigoid have been occasionally attributed to drug therapy. We conducted a multicenter prospective case-control study looking at the drugs used on a long-term basis before the onset of the disease in 116 incident cases of bullous pemphigoid and 216 control patients with malignant or benign skin tumors. Case patients and control patients received many drugs on a long-term basis (mean +/-SD, 4.4+/-3.2 and 4.4+/-2.7 years respectively). Two classes of drugs, neuroleptics and diuretics, were used more frequently by case patients than control patients. Neuroleptics were used by 15.5% of case patients and 8.3% of control patients (adjusted odds ratios; 1.9; 95% confidence interval, 0.95 to 3.8). Diuretics were used by 36.2% of case patients and 24.5% of control patients (adjusted odds ratios, 1.8; 95% confidence interval, 1.1 to 2.9). Among neuroleptics, no specific drug emerged. The association with diuretics was only linked to aldosterone antagonists, which were taken by 12.9% of case patients and 4.6% of control patients (adjusted odds ratios, 3.1; 95% confidence interval, 1....Continue Reading

Citations

May 15, 1998·The British Journal of Dermatology·S BoulinguezJ M Bonnetblanc
Aug 24, 1999·Clinical and Experimental Dermatology·T P MillardJ N Barker
Apr 16, 2002·Journal of the European Academy of Dermatology and Venereology : JEADV·K BazA Koca
Sep 8, 2007·Dermatology : International Journal for Clinical and Investigative Dermatology·Nadège CordelUNKNOWN French Study Group of Bullous Diseases
Aug 1, 2014·Wiener medizinische Wochenschrift·Andrea Kneisel, Michael Hertl
Nov 2, 2007·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Laurence Valeyrie-AllanoreJean-Claude Roujeau
Dec 15, 2012·Lancet·Enno Schmidt, Detlef Zillikens
May 9, 2012·Immunology and Allergy Clinics of North America·Enno SchmidtLuca Borradori
Dec 6, 2011·Clinics in Dermatology·Suzana Ljubojevic, Jasna Lipozenčić
Dec 6, 2011·Clinics in Dermatology·Giovanni Di ZenzoLuca Borradori
May 25, 2011·Dermatologic Clinics·Enno SchmidtLuca Borradori
Sep 14, 2010·La Presse médicale·Nathalie Bénéton-Benhard
Oct 6, 2009·Annales de dermatologie et de vénéréologie·V Doffoel-HantzC Bédane
Mar 16, 2012·The Journal of Investigative Dermatology·Pascal JolyJacques Bénichou
Nov 19, 2010·The Journal of Investigative Dermatology·Sinéad M LanganJoe West
Dec 28, 2007·Advances in Dermatology·Giovanni Di ZenzoLuca Borradori
Jan 17, 2007·Journal of the American Academy of Dermatology·Frederick A PereiraDavid M Rosmarin
Jul 24, 2004·Journal of the American Geriatrics Society·Carlos Fernandez-ViaderoDamaso Crespo Santiago
Jul 2, 2009·The British Journal of Dermatology·G MarazzaUNKNOWN Autoimmune bullous disease Swiss study group
Feb 10, 2009·International Journal of Dermatology·Aikaterini PatsatsiDimitrios Sotiriadis
Dec 17, 2008·Dermatologic Therapy·Laura AtzoriNicola Aste
Sep 13, 2006·The British Journal of Dermatology·A Kalińska-BieniasC Kowalewski
Nov 6, 2012·The British Journal of Dermatology·V A VenningG Kirtschig
Jun 1, 2011·Clinical and Experimental Dermatology·J KlukT M Finch
Aug 21, 2012·The Journal of Dermatology·Hui-Jun MaLian-Jin Song
Apr 22, 2011·International Journal of Dermatology·Kui Young ParkMyeung Nam Kim
Jan 11, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·P G StavropoulosC Antoniou
Oct 15, 2010·The Journal of Investigative Dermatology·Sylvie Bastuji-GarinUNKNOWN French Study Group for Bullous Diseases
Jul 20, 1999·Dermatologic Clinics·A N Crowson, C M Magro
Oct 6, 2015·Journal of the European Academy of Dermatology and Venereology : JEADV·D D OhD F Murrell
Jun 26, 2015·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Enno SchmidtAlexander Nast
Jul 24, 2013·Clinical & Developmental Immunology·Allan Seppänen
Dec 3, 1999·The British Journal of Dermatology·S RaultP Bernard
Jan 16, 2015·Archives of Dermatological Research·Erkan AlpsoySoner Uzun
Oct 21, 2003·The Annals of Pharmacotherapy·Burhan A AksakalMehmet Ali Gürer
Nov 22, 2016·The British Journal of Dermatology·C W X TanH Y Lee
May 4, 2017·Neuro-degenerative Diseases·Ai-Ling ShenChe-Yi Chou

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