Drugs for behavior disorders after traumatic brain injury: Systematic review and expert consensus leading to French recommendations for good practice

Annals of Physical and Rehabilitation Medicine
David PlantierSOFMER group

Abstract

There are no handbook or recommendations for the use of pharmacological agents to treat neurobehavioral disorders after traumatic brain injury (TBI). This work proposes a systematic review of the literature and a user guide on neuroleptics, antidepressants, beta-blockers, mood stabilizers and other medications for irritability, aggressiveness, agitation, impulsivity, depression, apathy… Steering, working and reading groups (62 people) were formed under the control of the French High Authority for Health (HAS) in collaboration with the SOFMER scientific society (French Society of Physical and Rehabilitation Medicine). Articles were searched by HAS officers in the Medline database from 1990 to 2012, crossing TBI and pharmacological agents. The HAS method to select, read and analyze papers is close to the PRISMA statements. Out of 772 references, 89 were analyzed, covering a total of 1306 people with TBI. There is insufficient evidence to standardize drug treatments for these disorders. There are however some elements to establish consensus recommendations for good clinical practice. Propranolol can improve aggression (B grade). Carbamazepine and valproate seem effective on agitation and aggression and are recommended as first lin...Continue Reading

References

Aug 1, 1991·Journal of Clinical Psychopharmacology·C T Gualtieri
Oct 1, 1988·Brain Injury : [BI]·M C ChandlerC T Gualtieri
Feb 1, 1988·American Journal of Physical Medicine & Rehabilitation·W J MysiwJ D Corrigan
Sep 1, 1985·The American Journal of Psychiatry·J A Mattes
Oct 1, 1995·The American Journal of Psychiatry·J R FannP C Esselman
Jan 1, 1995·The Journal of Neuropsychiatry and Clinical Neurosciences·R S MarinB Krupp
Nov 1, 1994·Brain Injury : [BI]·J L NickelsT M Wong
Apr 1, 1994·Journal of Clinical Psychopharmacology·S W StanislavA Childs
Jun 1, 1993·Journal of Clinical Psychopharmacology·M L MichalsA Childs
Oct 1, 1993·The American Journal of Psychiatry·S E Arnold
Oct 1, 1993·Neurology·M Weller, J Kornhuber
Jun 1, 1996·Intensive Care Medicine·J L Perez-VelaE Alted Lopez
Jan 1, 1996·The Journal of Neuropsychiatry and Clinical Neurosciences·P E Chatham-Showalter
Jan 28, 1998·Journal of Neurosurgical Sciences·I GóscínskiA Partyk
Mar 4, 1998·Brain Injury : [BI]·R KantA Pivovarnik
Apr 21, 1998·The Journal of Neuropsychiatry and Clinical Neurosciences·J C Holzer
Jul 8, 1998·Brain Injury : [BI]·R D ZafonteN R Mann
Sep 2, 1998·Brain Injury : [BI]·R KantD Zeiler
Nov 27, 1999·Brain Injury : [BI]·U MüllerD Y von Cramon
Jan 11, 2000·Brain Injury : [BI]·R WilkinsonS Guin-Renfroe
Apr 12, 2000·Brain Injury : [BI]·S W Stanislav, A Childs
Mar 30, 2001·The Journal of Head Trauma Rehabilitation·R D ZafonteN Cullen
Jul 10, 2003·Brain Injury : [BI]·Arlin PachetShaun Gray
Aug 21, 2003·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Kouichi KanetaniShunkichi Endo
Oct 21, 2003·American Journal of Physical Medicine & Rehabilitation·Margaret S WilsonRobert J Hamm
Jan 21, 2004·CNS Drugs·Melinda J BarkerSimon F Crowe
Jul 28, 2004·International Review of Psychiatry·Hochang B LeeVani Rao
Sep 1, 2004·The Psychiatric Quarterly·Leslie Citrome
Sep 24, 2004·Epilepsy & Behavior : E&B·Dieter Schmidt, Christian E Elger
Apr 7, 2005·Journal of Clinical Pharmacy and Therapeutics·H Leone, B W Polsonetti
Apr 14, 2005·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Ryan DeMarchiShree Bhalerao

❮ Previous
Next ❯

Citations

Nov 12, 2016·The Psychiatric Clinics of North America·Jonathan M MeyerStephen M Stahl
Sep 12, 2018·JBI Database of Systematic Reviews and Implementation Reports·Fiona J ClayMalcolm Hopwood
Sep 14, 2017·JBI Database of Systematic Reviews and Implementation Reports·Fiona J ClayMalcolm Hopwood
Dec 1, 2018·The Journal of Head Trauma Rehabilitation·Tiphaine BourseauMickaël Dinomais
Mar 1, 2018·Arquivos de neuro-psiquiatria·Renato AnghinahJéssica Natuline Ianof
May 28, 2019·Journal of Neurotrauma·Pavel N LizhnyakAndrew K Ottens
Jul 25, 2020·Neurological Research·Gary L Hoover, Victoria C Whitehair
Mar 19, 2020·The Journal of Nervous and Mental Disease·Joel Yager
Aug 1, 2018·American Journal of Physical Medicine & Rehabilitation·Lawrence R RobinsonHomer Tien
Nov 24, 2020·The Mental Health Clinician·Sophie Robert
Oct 28, 2020·Journal of Neuroscience Research·Joshua P McGeownRobert Borotkanics
Feb 25, 2021·Journal of Neural Transmission·Wojciech DanyszPeter Riederer
Mar 9, 2021·Fortschritte der Neurologie-Psychiatrie·Steffen AschenbrennerMagdalena Bossert
Nov 17, 2020·Psychosomatics·Idris LepplaMark A Oldham
Mar 23, 2021·Frontiers in Behavioral Neuroscience·Taylor A McCorkleRamesh Raghupathi
Sep 9, 2020·The Journal of Head Trauma Rehabilitation·Adam McKayJennie Ponsford
Jun 8, 2021·Journal of the Academy of Consultation-Liaison Psychiatry·Gustavo C MedeirosDurga Roy

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here

Related Papers

Annales de réadaptation et de médecine physique : revue scientifique de la Société française de rééducation fonctionnelle de réadaptation et de médecine physique
P Ribinik
Archives of Physical Medicine and Rehabilitation
Keith D CiceronePhilip A Morse
© 2022 Meta ULC. All rights reserved