Drugs for treating paracoccidioidomycosis.

The Cochrane Database of Systematic Reviews
V M MenezesC J F Fontes

Abstract

Paracoccidioidomycosis is a fungal infection found in particular geographic localities in Latin America. Treatment can last for up to two years is often associated with complications, including relapse, but people may die without it. To evaluate drugs used for treating paracoccidioidomycosis. We searched the Cochrane Infectious Diseases Group Specialized Register (January 2006), CENTRAL (The Cochrane Library 2005, Issue 4), PubMed (1966 to January 2006), EMBASE (1974 to January 2006), LILACS (1982 to January 2006), conference proceedings, and reference lists. We also contacted researchers and pharmaceutical companies. Randomized controlled trials comparing drugs for treating people with paracoccidioidomycosis. Two authors independently assessed trial eligibility and methodological quality, and extracted data, including adverse events. One trial with 42 participants met the inclusion criteria that compared imidazoles (itraconazole and ketoconazole) with sulfadiazine. No difference was detected for cure or clinical improvement, or serological titres after 10 months of treatment, and there was no difference detected in adverse events. The small number of participants and the short follow-up period impede definitive conclusions.

References

Jul 1, 1991·Revista Do Instituto De Medicina Tropical De São Paulo·G M Del NegroC da S Lacaz
Jan 1, 1990·Journal of Medical and Veterinary Mycology : Bi-monthly Publication of the International Society for Human and Animal Mycology·M S NaranjoA Restrepo
Jan 1, 1987·Reviews of Infectious Diseases·R NegroniR L Galimberti
Mar 1, 1987·Revista Do Instituto De Medicina Tropical De São Paulo·F UribeA Restrepo
Apr 1, 1987·Revista Da Sociedade Brasileira De Medicina Tropical·M FrancoN G Mota
Jul 1, 1986·Revista Do Instituto De Medicina Tropical De São Paulo·N L DillonP R Curi
Dec 19, 1986·JAMA : the Journal of the American Medical Association·W BrummundJ A Arkins
Mar 1, 1984·Revista Do Instituto De Medicina Tropical De São Paulo·J MarcondesJ Morceli
Jul 1, 1980·Reviews of Infectious Diseases·R NegroniR Galimberti
Nov 1, 1981·Clinical and Experimental Dermatology·D S Jolliffe, Y L Ngai
Jan 24, 1983·The American Journal of Medicine·A RestrepoM A Robledo
Apr 22, 1983·Mycopathologia·A T Londero, I S Melo
Sep 1, 1994·Journal of the American Academy of Dermatology·A Restrepo
Dec 1, 1993·International Journal of Dermatology·R Negroni
Apr 1, 1993·Clinical Microbiology Reviews·E BrummerA Restrepo
Nov 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L Z Goldani, A M Sugar
Nov 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·B J MannsH R Rabin
May 15, 2001·Epidemiology and Infection·D CalleA Restrepo
Jul 7, 2001·BMJ : British Medical Journal·P JüniM Egger
Jan 22, 2002·The Journal of Antimicrobial Chemotherapy·Jill Adler-Moore, Richard T Proffitt
Jan 30, 2002·The Journal of Antimicrobial Chemotherapy·Georg Maschmeyer
Sep 17, 2002·Medical Mycology·M A Shikanai-YasudaD R Andrade
Sep 24, 2002·Cadernos de saúde pública·Ziadir Francisco CoutinhoBodo Wanke
Aug 26, 2003·Revista Da Sociedade Brasileira De Medicina Tropical·Anamaria Mello Miranda PaniagoBodo Wanke
Aug 3, 2004·Revista Do Instituto De Medicina Tropical De São Paulo·Ricardo Mendes PereiraAntonia Teresinha Tresoldi
Nov 9, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Flavio Queiroz-TellesMaria A Shikanai-Yasuda

❮ Previous
Next ❯

Citations

Nov 9, 2007·Médecine et maladies infectieuses·A BousquetP Boiron
Jun 19, 2014·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·B RammaertO Lortholary
Apr 3, 2012·Medical Mycology Journal·Hanako KuraiKatsuhiko Kamei
Jan 7, 2020·Antonie van Leeuwenhoek·Lauana Aparecida SantosLuiz Cosme Cotta Malaquias

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Medical Case Reports
Pedro Francisco Ferraz de ArrudaMoacir Fernandes de Godoy
Revista iberoamericana de micología
Moira TaiczGriselda Berberian
Journal of the European Academy of Dermatology and Venereology : JEADV
M García BustínduyR García Montelongo
© 2022 Meta ULC. All rights reserved