Dual-Energy Computed Tomography-Based Display of Bone Marrow Edema in Incidental Vertebral Compression Fractures: Diagnostic Accuracy and Characterization in Oncological Patients Undergoing Routine Staging Computed Tomography

Investigative Radiology
Claudia FrellesenJulian L Wichmann

Abstract

The aim of this study was to evaluate the diagnostic performance of virtual noncalcium (VNCa) dual-energy computed tomography (DECT) reconstructions enabling visualization of bone marrow edema for characterization of incidental thoracolumbar compression fractures in routine thoracoabdominal staging computed tomography (CT). We retrospectively analyzed 51 oncological patients without suspected fracture or indicative complaints presenting at least 1 thoracolumbar compression fracture on routine thoracoabdominal staging DECT who had been examined between October 2015 and June 2017 using third-generation dual-source CT, had a previous CT within 3 months before, and also had undergone additional magnetic resonance imaging within 14 days, which served as the standard of reference. Three independent and blinded radiologists initially evaluated all vertebrae on conventional grayscale DECT series; after at least 8 weeks, observers reevaluated all cases using grayscale and color-coded VNCa DECT images. The age of each fracture was determined as either acute, chronic, or inconclusive. Specificity, sensitivity, and intraobserver and interobserver agreements were calculated taking into account clustering. A total of 98 vertebral compression...Continue Reading

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Citations

Feb 12, 2020·AJR. American Journal of Roentgenology·Veronique C M L TimmerAlida A Postma
Jan 28, 2020·Investigative Radiology·Kishore RajendranCynthia H McCollough
Mar 27, 2020·Investigative Radiology·Hatem Alkadhi, André Euler
Mar 29, 2019·The British Journal of Radiology·Tommaso D'AngeloJulian L Wichmann
Feb 4, 2021·European Journal of Radiology Open·Amit GuptaKai R Laukamp
Sep 4, 2021·European Radiology Experimental·Tommaso D'AngeloChristian Booz

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