Dual-energy computed tomography with advanced postimage acquisition data processing: improved determination of urinary stone composition

Journal of Endourology
Michael N FerrandinoGlenn M Preminger

Abstract

The characterization of urinary calculi using noninvasive methods has the potential to affect clinical management. CT remains the gold standard for diagnosis of urinary calculi, but has not reliably differentiated varying stone compositions. Dual-energy CT (DECT) has emerged as a technology to improve CT characterization of anatomic structures. This study aims to assess the ability of DECT to accurately discriminate between different types of urinary calculi in an in vitro model using novel postimage acquisition data processing techniques. Fifty urinary calculi were assessed, of which 44 had >or=60% composition of one component. DECT was performed utilizing 64-slice multidetector CT. The attenuation profiles of the lower-energy (DECT-Low) and higher-energy (DECT-High) datasets were used to investigate whether differences could be seen between different stone compositions. Postimage acquisition processing allowed for identification of the main different chemical compositions of urinary calculi: brushite, calcium oxalate-calcium phosphate, struvite, cystine, and uric acid. Statistical analysis demonstrated that this processing identified all stone compositions without obvious graphical overlap. Dual-energy multidetector CT with p...Continue Reading

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Citations

Feb 19, 2013·BMC Urology·Marco RosaUNKNOWN International Translational Research in Uro-Sciences Team (ITRUST)
Nov 29, 2015·Urolithiasis·Kim Hovgaard AndreassenPalle Joern Sloth Osther
Feb 16, 2013·Actas urologicas españolas·I Nuño de la RosaE Esteban
Nov 28, 2012·The Urologic Clinics of North America·Michael E Lipkin, Glenn M Preminger
Dec 22, 2015·Case Reports in Radiology·William E HaleyCynthia H McCollough
Aug 2, 2014·World Journal of Urology·Andreas NeisiusThomas Knoll
Jun 3, 2010·The Journal of Rheumatology·Bharath Manu Akkara Veetil, Tim Bongartz
Dec 8, 2010·Nature Reviews. Urology·Kittinut Kijvikai, J J M de la Rosette
Feb 10, 2011·Nature Reviews. Urology·Hans-Göran Tiselius
Jan 22, 2011·Current Opinion in Urology·Cecilia M CraccoRoberto M Scarpa

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Methods Mentioned

BETA
infrared spectroscopy
X-ray

Software Mentioned

Syngo ® Multi Modality Workplace
Stone Window
SPSS
DECT

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