Dual-Energy CT-Based Differentiation of Benign Posttreatment Changes From Primary or Recurrent Malignancy of the Head and Neck: Comparison of Spectral Hounsfield Units at 40 and 70 keV and Iodine Concentration

AJR. American Journal of Roentgenology
Hideomi YamauchiAshok Srinivasan

Abstract

The goals of our study were to evaluate dual-energy CT (DECT) differences between benign posttreatment changes and primary or recurrent head and neck malignancies in terms of spectral Hounsfield units for virtual monochromatic series at 40 keV and iodine concentration and compare their utility with that of spectral Hounsfield units at 70 keV. A retrospective review of patients with a history of head and neck malignancy evaluated with DECT of the neck from November 2012 through December 2014 revealed 16 patients with benign posttreatment changes and 24 with malignancies (17 primary tumors and seven recurrent tumors). One reader placed ROIs within benign posttreatment changes or malignant tumors in each patient to generate spectral Hounsfield units at 40 keV, iodine concentration, and spectral Hounsfield units at 70 keV, and the Wilcoxon rank sum test was used to evaluate the differences between the two cohorts. ROC curves were also generated, and AUC and partial AUC were calculated at the three following specificities: 75%, 80%, and 90%. Malignant tissues were significantly different from benign posttreatment changes in spectral Hounsfield units at 40 keV (p < 0.0001), iodine concentration (p < 0.0001), and spectral Hounsfield u...Continue Reading

References

Oct 1, 1977·Journal of Computer Assisted Tomography·R A Brooks
Jan 1, 1976·Neuroradiology·R A RutherfordI Isherwood
Jan 1, 1976·Neuroradiology·R A RutherfordI Isherwood
Dec 1, 1973·The British Journal of Radiology·G N Hounsfield
Dec 8, 2006·European Radiology·Thorsten R C JohnsonChristoph R Becker
May 25, 2011·AJR. American Journal of Roentgenology·Hersh ChandaranaMichael Macari
Sep 21, 2013·Journal of Computer Assisted Tomography·Ashok SrinivasanSuresh K Mukherji
Jan 1, 2014·Journal of Computer Assisted Tomography·Guangli WangWei Li

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Citations

Aug 10, 2018·Acta Radiologica·Saravanabavaan SuntharalingamKai Nassenstein
Dec 19, 2018·Head & Neck·Do Hyung LeeKyung-Sook Yang
Jun 15, 2017·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Julius Griauzde, Ashok Srinivasan
Jun 11, 2019·Expert Review of Anticancer Therapy·Reza Forghani
Mar 28, 2020·Medical Physics·Cynthia H McColloughNorbert J Pelc
Apr 25, 2017·Current Radiology Reports·Elise D RoeleA A Postma
Jan 12, 2020·La Radiologia medica·Giuseppe CiceroSilvio Mazziotti
Feb 4, 2021·European Journal of Radiology Open·Amit GuptaKai R Laukamp
Dec 9, 2020·Technology and Health Care : Official Journal of the European Society for Engineering and Medicine·Yi-Chuan MaAi-Qi Chen
Jun 5, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Karen Buch
Jun 24, 2021·European Radiology Experimental·Vanja HarsakerAnne Catrine Martinsen
Sep 3, 2021·Journal of Applied Clinical Medical Physics·Crystal A GreenEhsan Samei
Jun 16, 2018·Dental Clinics of North America·Anita GohelOsamu Sakai

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