Dual-energy CT in patients with colorectal cancer: Improved assessment of hypoattenuating liver metastases using noise-optimized virtual monoenergetic imaging

European Journal of Radiology
Lukas LengaSimon S Martin

Abstract

To assess the value of the noise-optimized virtual monoenergetic imaging (VMI+) technique on quantitative and qualitative image parameters in patients with hypoattenuating liver metastases from colorectal cancer (CRC) at abdominal dual-energy CT (DECT). Fifty-three consecutive patients (mean age, 70.3 ± 11.4 years; range, 44-86 years) with histologically proven, hypoattenuating liver metastases from CRC were retrospectively included in this IRB-approved study. DECT datasets were reconstructed as standard linearly-blended M_0.6 image series, traditional virtual monoenergetic images (VMI), and noise-optimized VMI+ series. VMI and VMI+ reconstructions were obtained at energy levels ranging from 40 to 100-keV with 10-keV increments. Signal attenuation of liver parenchyma and liver metastases was measured to calculate signal-to-noise (SNR) and contrast-to-noise (CNR) ratios. Each image series was subjectively rated by three blinded radiologists with regard to image quality, lesion delineation, and image noise using a five-point Likert scale. Quantitative image quality parameters peaked at 40-keV VMI+ (SNR, 8.1 ± 3.4; CNR, 6.5 ± 2.6) with statistically significant differences in comparison with standard reconstructions and all tradit...Continue Reading

Citations

Apr 27, 2019·Der Radiologe·Christian Krestan
Nov 16, 2019·Abdominal Radiology·Tugce Agirlar TrabzonluVahid Yaghmai
Jun 30, 2019·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Joyce van SluisWalter Noordzij

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