Dual energy CT in patients with polycystic kidney disease.

European Radiology
Nikolaus ArndtAnno Graser

Abstract

To evaluate the diagnostic efficacy of dual source-dual energy CT (DECT) in the detection of neoplasia in patients with polycystic kidney disease (PKD). A total of 21 patients with PKD underwent DECT on a dual source system, using kVp settings of Sn140/100 or 140/80. Colour-coded iodine maps and virtual unenhanced images were used to determine enhancement within cysts and to differentiate haemorrhagic from simple cysts. A cut-off of 15 HU was used as a threshold for malignancy. In patients with malignancy, histopathology was the gold standard; otherwise, patients underwent follow-up imaging for 150-908 days. On the basis of measured enhancement, 13 enhancing masses were seen in 4 patients (12 renal cell cancers and 1 adenoma); follow-up imaging showed no malignancy in 18 patients. Cysts did not enhance by more than 15 HU, whereas masses showed a mean enhancement of 45 (25-123) HU. Average radiation exposure was 9.6 mSv for the biphasic protocol and 5.8 mSv for DECT only. DECT greatly facilitates the detection of malignancy in patients with polycystic kidney disease, at the same time reducing radiation exposure by omission of a true unenhanced phase. • Identification of tumours within polycystic kidneys can be difficult. ...Continue Reading

References

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Citations

Apr 11, 2013·Der Urologe. Ausg. A·D-A ClevertA Graser
Oct 5, 2013·European Radiology·Achille MiletoDaniel T Boll
Jan 10, 2014·European Radiology·David SimonsHeinz-Peter Schlemmer
Mar 3, 2015·AJR. American Journal of Roentgenology·Achille MiletoDaniele Marin
Jan 28, 2017·Radiologic Clinics of North America·Achille Mileto, Daniele Marin
Mar 6, 2019·AJR. American Journal of Roentgenology·Davide BelliniAchille Mileto
Jun 5, 2016·Current Opinion in Urology·Katherine M Krajewski, Atul B Shinagare
Mar 28, 2020·Medical Physics·Cynthia H McColloughNorbert J Pelc
Jul 18, 2014·Journal of Computer Assisted Tomography·Jijo PaulEmmanuel C Mbalisike

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