PMID: 589476Dec 16, 1977

Dual excitatory inputs to caudate spiny neurons from substantia nigra stimulation

Brain Research
J D Kocsis, S T Kitai

Abstract

In the present set of experiments of two component excitatory postsynaptic potential (EPSP) (fast and slow) was recorded from caudate (Cd) neurons after substantia nigra (SN) stimulation in the alpha-chloralose anesthetized cat. Several unique properties of the fast response are demonstrated and used to determine certain functional properties of Cd neurons. The following conclusions have been drawn from these experiments. (1) A dual excitatory innervation pattern (fast and slow) exists to the Cd from SN stimulation. (2) The fast system is independent of the Cd efferent system. (3) Neurons receiving this dual input are spine laden neurons. (4) Dendritic inhibition is operating on these neurons and often has little or no direct influence on the observed soma membrane potential. The dendritic inhibition reduced test EPSP amplitude for several hundred milliseconds for all Cd afferents except for the fast SN input. Such a decoupling of the fast input from the inhibition may play an important role in Cd signal processing.

References

Apr 1, 1977·Brain Research·J D KocsisS T Kitai
Feb 26, 1976·Experimental Brain Research·S T KitaiJ D Kocsis
Jan 1, 1971·Acta Physiologica Scandinavica. Supplementum·U Ungerstedt
Sep 30, 1971·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J M Kemp, T P Powell
Jul 1, 1974·The Journal of Comparative Neurology·L C ConradD W Pfaff
Jan 1, 1972·The Journal of Comparative Neurology·M B Carpenter, P Peter
Nov 1, 1967·Brain Research·T L Frigyesi, D P Purpura

Citations

Jan 1, 1986·Experimental Brain Research·L J RyanP M Groves
Nov 7, 2006·Psychopharmacology·Christopher C LapishJeremy K Seamans
Oct 1, 1985·Journal of Neuroscience Methods·M A Ariano, S L Kenny
Jan 1, 1980·Progress in Neurobiology·A Dray
Nov 1, 1978·Brain Research Bulletin·C P VandermaelenS T Kitai
Sep 1, 1980·Brain Research Bulletin·G A BishopJ S King
Jan 1, 1984·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·S A Bayer
Dec 28, 2011·The Journal of General Physiology·John I Broussard
May 11, 1981·Brain Research·J W LighthallS T Kitai
Feb 24, 2015·Progress in Neurobiology·K L Eskow JaunarajsA Pisani

Related Concepts

Afferent Pathways
Felis catus
Caudate Nucleus Structure
Dendrites
Motor Pathways
Neural Inhibition
Neurons
Reaction Time
Substantia Nigra Structure

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.