Dual Probe Sensors Using Atomically Precise Noble Metal Clusters

ACS Omega
Vidhya SubramanianThalappil Pradeep

Abstract

This article adds a new direction to the functional capability of protein-protected atomically precise gold clusters as sensors. Counting on the extensively researched intense luminescence of these clusters and considering the electron donating nature of select amino acids, we introduce a dual probe sensor capable of sensing changes in luminescence and conductivity, utilizing bovine serum albumin-protected atomically precise gold clusters hosted on nanofibers. To this end, we have also developed a hybrid nanofiber with a conducting core with a porous dielectric shell. We show that clusters in combination with nanofibers offer a highly selective and sensitive platform for the detection of trace quantities of trinitrotoluene, both in solution and in the vapor phase. In the solution phase, trinitrotoluene (TNT) can be detected down to 1 ppt at room temperature, whereas in vapor phase, 4.8 × 109 molecules of TNT can be sensed using a 1 mm fiber. Although the development in electrospinning techniques for fabricating nanofibers as sensors is quite substantial, a hybrid fiber with the dual properties of conductivity and luminescence has not been reported yet.

References

Jan 27, 1962·Nature·B ROSENBERG
Dec 15, 2010·The Analyst·C V DurgadasK Sreenivasan
Oct 21, 2011·ACS Nano·Kamalesh ChaudhariThalappil Pradeep
Feb 7, 2012·ACS Applied Materials & Interfaces·Clemonne J MadadrangShifeng Hou
Dec 20, 2013·Accounts of Chemical Research·Seiji YamazoeTatsuya Tsukuda
Oct 3, 2014·Analytical Chemistry·Li-Yi ChenHuan-Tsung Chang
Oct 23, 2014·Analytical Chemistry·Atanu GhoshThalappil Pradeep
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Jun 9, 2017·ACS Nano·Kaiyuan ZhengJianping Xie

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Citations

Dec 12, 2018·Nanoscale·Kamalesh ChaudhariThalappil Pradeep
Nov 10, 2020·Small·Habib Gholipour-RanjbarJulia Laskin
Dec 15, 2020·Journal of Drug Targeting·Pawandeep Kaur, Diptiman Choudhury
Jan 30, 2021·ACS Applied Materials & Interfaces·Debasmita GhoshThalappil Pradeep
May 14, 2021·Advanced Materials·Yingwei LiRongchao Jin

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Methods Mentioned

BETA
transmission electron microscopy
scanning
X-ray
fluorescence microscopy

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