Dual role of p-tosylchloride: copper-catalyzed sulfenylation and metal free methylthiolation of imidazo[1,2-a]pyridines

Organic & Biomolecular Chemistry
Chitrakar RaviSubbarayappa Adimurthy

Abstract

Copper-catalyzed regioselective C-3 sulfenylation of imidazo[1,2-a]pyridines using p-tosylchloride as a benign source of sulfenylating agents has been developed. On the other hand, p-tosylchloride mediated thiomethylation of imidazo[1,2-a]pyridines with dimethylsulfoxide as a source of thiomethylation under metal-free conditions was also described.

References

Oct 25, 2002·Cardiovascular Drug Reviews·Katsufumi MizushigeHitoshi Suzuki
Sep 28, 2007·Mini Reviews in Medicinal Chemistry·Cécile Enguehard-Gueiffier, Alain Gueiffier
Jul 2, 2009·Chemical Communications : Chem Comm·Olivier Baslé, Chao-Jun Li
Jul 14, 2011·Chemical Communications : Chem Comm·Qian WuJingsong You
Jan 8, 2013·The Journal of Organic Chemistry·Darapaneni Chandra MohanSubbarayappa Adimurthy
May 20, 2014·Organic Letters·Chitrakar RaviSubbarayappa Adimurthy
Oct 14, 2014·Chemical Society Reviews·Chao ShenXiaogang Liu
Oct 29, 2014·The Journal of Organic Chemistry·Ramachandra Reddy DonthiriSubbarayappa Adimurthy
Feb 11, 2015·Chemical Communications : Chem Comm·Sheng-Yi YanBing-Feng Shi
Mar 21, 2015·The Journal of Organic Chemistry·Poonam SharmaNidhi Jain

❮ Previous
Next ❯

Citations

Sep 30, 2016·The Journal of Organic Chemistry·Abhisek JoshiSubbarayappa Adimurthy
Sep 24, 2016·The Journal of Organic Chemistry·Chitrakar RaviSubbarayappa Adimurthy
Mar 21, 2017·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Chitrakar Ravi, Subbarayappa Adimurthy
Feb 10, 2017·Organic & Biomolecular Chemistry·Dingyi WangYuanxing Wang
Nov 9, 2017·Organic & Biomolecular Chemistry·Supravat SamantaSubbarayappa Adimurthy
Nov 12, 2019·Acta Crystallographica. Section E, Crystallographic Communications·Hussien Ahmed KhameesMahendra Madegowda
Jul 28, 2021·Chemical Communications : Chem Comm·Narendra R Chaubey, Anant R Kapdi
Sep 20, 2019·The Journal of Organic Chemistry·Poonam Sharma, Nidhi Jain
Dec 19, 2018·The Journal of Organic Chemistry·Rashmi SemwalSubbarayappa Adimurthy
Aug 31, 2018·The Journal of Organic Chemistry·Hiroki IidaRyoma Ohkado
Aug 31, 2021·Angewandte Chemie·Heng LiuQing-An Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved