Dual task effect on postural control in patients with degenerative cerebellar disorders

Cerebellum & Ataxias
Heike JacobiDagmar Timmann

Abstract

The cerebellum plays an important role for balance control and the coordination of voluntary movements. Beyond that there is growing evidence that the cerebellum is also involved in cognitive functions. How ataxic motor symptoms are influenced by simultaneous performance of a cognitive task, however, has rarely been assessed and some of the findings are contradictory. We assessed stance in 20 patients with adult onset degenerative almost purely cerebellar disorders and 20 healthy controls during single and dual task conditions (verbal working memory task). To objectively measure postural sway and the impact of somatosensory, visual and vestibular inputs we used static and dynamic posturography with the Sensory Organization Test (SOT). In both groups, cerebellar patients and controls, dual tasking reduced all sway parameters. Reduction of sway path was higher in cerebellar patients and increased with the difficulty of the postural task. The frequency of falls was higher in the patients group especially during the more challenging conditions and dual task performance in particular increased the risk of falls in cerebellar patients. Dual task conditions had a larger impact on sway parameters in patients with chronic cerebellar dis...Continue Reading

References

Nov 1, 1996·Movement Disorders : Official Journal of the Movement Disorder Society·P GatevM Hallett
Jul 1, 1997·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·A Shumway-CookM Baldwin
Jan 1, 1997·International Review of Neurobiology·J D Schmahmann, D N Pandya
Mar 6, 2002·Journal of Neurophysiology·Catherine E Lang, Amy J Bastian
May 29, 2002·Neuroscience·M MolinariM G Leggio
Jun 5, 2003·Movement Disorders : Official Journal of the Movement Disorder Society·Roberta MarcheseGiovanni Abbruzzese
Dec 23, 2003·Journal of the American Geriatrics Society·Pamela L SheridanJeffrey M Hausdorff
Sep 24, 2005·The European Journal of Neuroscience·Galit YogevJeffrey M Hausdorff
Dec 1, 2005·Brain : a Journal of Neurology·Susan M RavizzaJulie A Fiez
Jun 14, 2006·Neurology·T Schmitz-HübschRoberto Fancellu
Mar 6, 2008·Nature Reviews. Neuroscience·Masao Ito
Oct 7, 2008·NeuroImage·Catherine J Stoodley, Jeremy D Schmahmann
Jun 27, 2009·Annual Review of Neuroscience·Peter L StrickJulie A Fiez
Oct 27, 2009·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Corrine Durisko, Julie A Fiez
Nov 20, 2009·Journal of the Neurological Sciences·Farid SalihChristoph J Ploner
Feb 16, 2010·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Catherine J Stoodley, Jeremy D Schmahmann
Aug 26, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Winfried IlgMatthis Synofzik
Sep 1, 1998·Trends in Cognitive Sciences·J E Desmond, J A Fiez
Mar 11, 2011·Experimental Brain Research·Tadayoshi Asaka, Yun Wang
Nov 6, 2012·Human Brain Mapping·Keren-Happuch EJohn E Desmond
Aug 24, 2013·Journal of Neurophysiology·Winfried IlgDagmar Timmann

❮ Previous
Next ❯

Citations

Aug 24, 2019·Journal of Applied Research in Intellectual Disabilities : JARID·Hiba KachouriSonia Sahli
Oct 18, 2020·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Ornella ArgentoUgo Nocentini

❮ Previous
Next ❯

Software Mentioned

SPSS
MATLAB

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.