Dual task interference on postural sway, postural transitions and gait in people with Parkinson's disease and freezing of gait

Gait & Posture
Ana Claudia de Souza FortalezaFay B Horak

Abstract

Freezing of gait (FoG) is associated with less automatic gait and more impaired cognition, balance and postural transitions compared to people with PD who do not have FoG. However, it is unknown whether dual-task cost during postural sway, postural transitions (such as gait initiation and turning), and gait are more in subjects with Parkinson's disease (PD) who have freezing of gait (FoG+) compared to those who do not have FoG (FoG-). Here, we hypothesized that the effects of a cognitive dual task on postural sway, postural transitions and gait would be larger in FoG+ than FoG-. Thirty FoG- and 24 FoG+ performed an Instrumented Stand and Walk test in OFF medication state, with and without a secondary cognitive task (serial subtraction by 3s). Measures of postural sway, gait initiation, turning, and walking were extracted using body-worn inertial sensors. FoG+ showed significantly larger dual task cost than FoG- for several gait metrics, but not during postural sway or postural transitions. During walking, FoG+ exhibited a larger dual task cost than FoG- resulting in shorter stride length and slower stride velocity. During standing, FoG+ showed a larger postural sway compared to FoG- and during gait initiation, FoG+, but not FoG...Continue Reading

Citations

Mar 21, 2018·Neurorehabilitation and Neural Repair·Esther M J BekkersAlice Nieuwboer
Oct 30, 2018·European Journal of Physical and Rehabilitation Medicine·Cira FundaròRoberto Casale
Oct 9, 2019·Journal of Parkinson's Disease·Sommer L Amundsen HuffmasterColum D MacKinnon
Sep 22, 2020·Movement Disorders : Official Journal of the Movement Disorder Society·Bianca Vieira-YanoCarla Silva-Batista
Sep 25, 2019·Sensors·Marco GhislieriValentina Agostini
Apr 24, 2020·Parkinson's Disease·Sabine JanssenRichard J A van Wezel
Mar 3, 2018·Frontiers in Aging Neuroscience·Christian SchlenstedtFay Horak
Jun 15, 2018·Frontiers in Neurology·Peter C FinoFay B Horak
Dec 24, 2018·Movement Disorders : Official Journal of the Movement Disorder Society·Moria DaganJeffrey M Hausdorff
Sep 12, 2019·Frontiers in Neurology·Erich Talamoni FonoffClement Hamani
Apr 7, 2020·Neurorehabilitation and Neural Repair·Laurie A KingFay B Horak
Oct 10, 2020·Human Brain Mapping·Carla Silva-BatistaOscar Miranda-Domínguez
Nov 2, 2020·Journal of Neuroengineering and Rehabilitation·Amy MaslivecWilliam Young
Feb 2, 2021·Journal of Parkinson's Disease·Sommer L Amundsen-HuffmasterColum D MacKinnon
Apr 26, 2021·Parkinsonism & Related Disorders·Sarah J OzingaJay L Alberts
Jul 22, 2021·Movement Disorders : Official Journal of the Movement Disorder Society·Elisabetta SarassoMassimo Filippi
Mar 29, 2020·Human Movement Science·Késia Maísa do Amaral-FelipeFlávia Roberta Faganello-Navega

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