journal cover

Dual threshold optimization and network inference reveal convergent evidence from TF binding locations and TF perturbation responses

Genome Research

Feb 16, 2020

Yiming KangMichael R Brent

Download from

Publisher
PubMed

Abstract

A high-confidence map of the direct, functional targets of each transcription factor (TF) requires convergent evidence from independent sources. Two significant sources of evidence are TF binding locations and the transcriptional responses to direct TF perturbations. Systematic data set...read more

Mentioned in this Paper

Location
Protein Domain
Chemical cofactor
DNA Transposable Elements
Transcription Factor
Genes
Yeasts
Analysis
Altretamine/Cisplatin/Cyclophosphamide/Misonidazole Protocol
Inference
9
Paper Details
References
  • References68
  • Citations1
12345...
  • References68
  • Citations1
1

Feeds With Similar Papers

Transposable Elements

Transposable elements (tes) have profound effects on the structure, function and evolution of their host genomes.

Extracellular Vesicle Analysis

Extracellular vesicles are cell-derived structures containing complex cargo, including proteins and nucleic acids, that originate from endosomal systems or the plasma membrane. Here is the latest research on technologies for the analysis of extracellular vesicles.

Transposons for Gene Editing

Transposons can replicate and spread through the host’s genome and therefore be used as a genetic tool for analysis of gene function. Discover the latest research on the use of transposons for gene editing here.

Structure and Function of DNA

The double helix structure of DNA is important for its biological function. Discover the latest research on the Structure and Function of DNA here.

© 2020 Meta ULC. All rights reserved

Dual threshold optimization and network inference reveal convergent evidence from TF binding locations and TF perturbation responses

Genome Research

Feb 16, 2020

Yiming KangMichael R Brent

PMID: 32060051

DOI: 10.1101/gr.259655.119

Abstract

A high-confidence map of the direct, functional targets of each transcription factor (TF) requires convergent evidence from independent sources. Two significant sources of evidence are TF binding locations and the transcriptional responses to direct TF perturbations. Systematic data set...read more

Mentioned in this Paper

Location
Protein Domain
Chemical cofactor
DNA Transposable Elements
Transcription Factor
Genes
Yeasts
Analysis
Altretamine/Cisplatin/Cyclophosphamide/Misonidazole Protocol
Inference
9

Feeds With Similar Papers

Transposable Elements

Transposable elements (tes) have profound effects on the structure, function and evolution of their host genomes.

Extracellular Vesicle Analysis

Extracellular vesicles are cell-derived structures containing complex cargo, including proteins and nucleic acids, that originate from endosomal systems or the plasma membrane. Here is the latest research on technologies for the analysis of extracellular vesicles.

Related Papers

Paper Details
References
  • References68
  • Citations1
12345...
  • References68
  • Citations1
1

Download from

Publisher
PubMed
/papers/dual-threshold-optimization-and-network-inference/32060051