Duodenum-preserving total and partial pancreatic head resection for benign tumors--systematic review and meta-analysis

Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Hans G BegerBertram Poch

Abstract

Potential benefits of local extirpation of benign pancreatic head tumors are tissue conservation of pancreas, stomach, duodenum and common bile duct (CBD) and maintenance of pancreatic functions. Medline/PubMed, Embase and Cochrane Library databases were searched to identify studies applying duodenum-preserving total or partial pancreatic-head resection (DPPHRt/p) and reporting short- and long-term outcomes. Twenty-four studies, including 416 patients who underwent DPPHRt/p, were identified for systematic analysis. The meta-analysis was based on 10 prospective controlled and 4 retrospective controlled cohort studies, comparing 293 DPPHRt/p resections with 372 pancreato-duodenectomies (PD). Of 416 patients, 75.7% underwent total and 24.3% partial head resection, while 47.1% included segmentectomy of duodenum and CBD. The most common pathology was cystic neoplasm (65.8%) and endocrine tumors (13.4%). The frequencies of severe postoperative complications of 8.8%, pancreatic fistula of 19.2%, re-operation of 1.7% and hospital mortality of 0.48%, indicate a low level of early post-operative complications. DPPHRt/p significantly preserved the level of exocrine (IV = -0.67, 95% CI -0.98 to -0.35, p = 0.0001) and endocrine (IV = 18.20,...Continue Reading

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Citations

Nov 4, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Hans G BegerBettina M Rau
May 25, 2016·Scandinavian Journal of Gastroenterology·Kjetil Søreide, Knut Jørgen Labori
Jan 24, 2019·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jiro KusakabeRyan C Fields
Feb 19, 2015·World Journal of Surgery·H G BegerM H Schoenberg
Nov 13, 2019·Langenbeck's Archives of Surgery·Michael S PärliKaspar Z'graggen
Oct 5, 2017·World Journal of Surgery·Yohann RenardReza Kianmanesh
Mar 25, 2019·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·Hans G BegerB Poch
Jan 28, 2020·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Hans G BegerBertram Poch

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