Durability of the sun protection factor provided by dihydroxyacetone

Photodermatology, Photoimmunology & Photomedicine
A Faurschou, Hans Christian Wulf

Abstract

The sunless tanning agent dihydroxyacetone (DHA) is known to protect against longwave ultraviolet radiation (UVA) and visible light. Recently, our laboratory has shown that DHA in addition offers a modest sun protection factor (SPF) in humans. We conducted this study in order to investigate the durability of the SPF provided by DHA. Ten healthy volunteers were treated with 20% DHA cream twice in three areas on the volar forearm. One, 5 and 7 days after the second application the participants were phototested with simulated sunlight in each area. Blue reflectance was used to measure the skin coloration by DHA in the test sites. DHA generated a significant SPF of 3.0 at day 1, 2.0 at day 5 and 1.7 at day 7 (P<0.0001). The SPF was positively correlated to the change in blue reflectance (r=0.39, P=0.034). The loss of SPF unit/day was not significantly different between the subjects (P<0.122). However, the intercepts were significantly different (P<0.0001) indicating differences in the initial SPF obtained among the subjects. The SPF of DHA decreases with the same loss of SPF unit/day between humans and the durability of the SPF thus depends on the initial SPF provided.

References

Jan 1, 1977·Advances in Experimental Medicine and Biology·T P LabuzaH C Warmbier
Jun 1, 1988·Archives of Dermatology·T B Fitzpatrick
Aug 1, 1996·Photodermatology, Photoimmunology & Photomedicine·J Lock-Andersen, H C Wulf
Sep 30, 1960·Science·E WITTGENSTEIN, H K BERRY
Jun 1, 1962·Archives of Dermatology·L GOLDMAN, D J BLANEY
Jul 21, 2004·Archives of Dermatology·Annesofie FaurschouHans Christian Wulf

❮ Previous
Next ❯

Citations

Dec 1, 2009·Pediatric Health·Leslie K DennisLinda G Snetselaar
Mar 4, 2009·Dermatologic Clinics·Raja K SivamaniRobert P Dellavalle
Aug 19, 2007·Lancet·Stephan LautenschlagerMark R Pittelkow
Sep 7, 2007·Photodermatology, Photoimmunology & Photomedicine·Brian KongshojHans Christian Wulf
Apr 2, 2008·International Journal of Dermatology·Natta RajatanavinSuthinee Kulkollakarn
Mar 16, 2011·International Journal of Cosmetic Science·T S BaloghA R Baby
May 23, 2006·Journal of the American Academy of Dermatology·Katie BrooksAlan C Geller
Aug 17, 2018·Photodermatology, Photoimmunology & Photomedicine·Katharina DiehlSven Schneider
Dec 2, 2017·Environmental Toxicology·Kelly R SmithNatalie R Gassman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of the American Academy of Dermatology
Jennifer M FuAllan C Halpern
Aesthetic Surgery Journal
Cindy J Rogers
© 2021 Meta ULC. All rights reserved