Duration of Breastfeeding and Risk of SIDS: An Individual Participant Data Meta-analysis

Pediatrics
John M D ThompsonFern R Hauck

Abstract

Sudden infant death syndrome (SIDS) is a leading cause of postneonatal infant mortality. Our previous meta-analyses showed that any breastfeeding is protective against SIDS with exclusive breastfeeding conferring a stronger effect.The duration of breastfeeding required to confer a protective effect is unknown. To assess the associations between breastfeeding duration and SIDS. Individual-level data from 8 case-control studies. Case-control SIDS studies with breastfeeding data. Breastfeeding variables, demographic factors, and other potential confounders were identified. Individual-study and pooled analyses were performed. A total of 2267 SIDS cases and 6837 control infants were included. In multivariable pooled analysis, breastfeeding for <2 months was not protective (adjusted odds ratio [aOR]: 0.91, 95% confidence interval [CI]: 0.68-1.22). Any breastfeeding ≥2 months was protective, with greater protection seen with increased duration (2-4 months: aOR: 0.60, 95% CI: 0.44-0.82; 4-6 months: aOR: 0.40, 95% CI: 0.26-0.63; and >6 months: aOR: 0.36, 95% CI: 0.22-0.61). Although exclusive breastfeeding for <2 months was not protective (aOR: 0.82, 95% CI: 0.59-1.14), longer periods were protective (2-4 months: aOR: 0.61, 95% CI: 0.42...Continue Reading

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Citations

Aug 24, 2018·Maternal & Child Nutrition·Melissa Bartick, Cecília Tomori
Oct 12, 2018·JAAPA : Official Journal of the American Academy of Physician Assistants·Mazal Maged, Denise Rizzolo
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Jun 23, 2021·Pediatrics·Michael H GoodsteinUNKNOWN COMMITTEE ON FETUS AND NEWBORN, TASK FORCE ON SUDDEN INFANT DEATH SYNDROME
Sep 27, 2018·Pediatrics·Alison Volpe Holmes

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