Duration of hepatitis E viremia in pregnancy

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
Nargis BegumPremashis Kar

Abstract

To investigate the duration of hepatitis E virus (HEV) infection in pregnant and non-pregnant women with acute viral hepatitis (AVH) or fulminant hepatic failure (FHF). A prospective study conducted with 20 pregnant women with AVH, 20 non-pregnant women with AVH, 10 pregnant women with FHF, and 9 non-pregnant women with FHF-all with HEV infection. The women were followed up on day 7, 15, 30, 60, and 90 following recruitment for the presence of HEV-RNA. Of the 59 patients with HEV infection, only 2 (3.4%) revealed HEV viremia at day 30 and none of the patients was viremic at day 60 and day 90. The proportion of HEV viremia in pregnant women with AVH and FHF at day 15 was significantly higher than in non-pregnant women (88.3% vs 27.6%; P<0.001). Similarly, HEV viremia among patients with AVH was significantly higher in pregnant women compared with non-pregnant women (100% vs 55%; P<0.001). HEV viremia may be prolonged in pregnancy.

References

Jan 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·S A TsarevR H Purcell
Oct 30, 1982·Lancet·A SmedileM Rizzetto
Feb 1, 1981·The American Journal of Medicine·M S KhurooM I Khuroo
Oct 1, 1995·The Journal of Infectious Diseases·E T ClaysonM P Shrestha
Jan 1, 1995·Gastroenterology·S K NandaS K Panda
Jan 16, 1993·Lancet·A ChauhanN K Ganguly
May 18, 2004·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·A KumarN S Murthy
Apr 21, 2007·Journal of Gastroenterology and Hepatology·Nishat JilaniPremashis Kar
Jul 30, 2008·Liver International : Official Journal of the International Association for the Study of the Liver·Udayakumar NavaneethanMohamed T Shata
Sep 13, 2008·The American Journal of Gastroenterology·Premashis KarBhudev C Das
Oct 18, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Vikram BhatiaSubrat Kumar Acharya
Mar 3, 2009·Journal of Health, Population, and Nutrition· Mamun-Al-MahtabFazal Karim
Jul 22, 2009·Virology Journal·Andrew A AdjeiTheophilus K Adiku

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Citations

May 23, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Valsan Philip Verghese, Joan L Robinson
Feb 18, 2012·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·R AntyA Tran
May 10, 2016·Expert Review of Gastroenterology & Hepatology·Rakesh Aggarwal, Amit Goel
Jan 15, 2014·The American Journal of Tropical Medicine and Hygiene·Lisa J KrainAlain B Labrique
May 8, 2018·Cold Spring Harbor Perspectives in Medicine·Rakesh Aggarwal, Amit Goel

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