Duration of major and minor depressive episodes and associated risk indicators in a psychiatric epidemiological cohort study of the general population

Acta Psychiatrica Scandinavica
Margreet Ten HaveRon de Graaf

Abstract

Hardly any studies exist on the duration of major depressive disorder (MDD) and factors that explain variations in episode duration that lack biases. This limits clinical decision-making and leaves patients wondering when they will recover. Data were used from the Netherlands Mental Health Survey and Incidence Study-2, a psychiatric epidemiological cohort study among a nationally representative adult population. Respondents with a newly originated depressive episode were selected: 286 MDD and 107 minor depressive disorder (MinDD) cases. DSM-IV diagnoses were assessed with the Composite International Diagnostic Interview 3.0 and episode duration with the Life Chart Interview. Among MDD cases, median episode duration was 6 months, mean duration was 10.7 months, and 12% had not recovered at 36 months. Longer duration was associated with comorbid dysthymia, anxiety disorder, psychotropic medication use (i.e. antidepressants or benzodiazepines prescribed by a mental health professional), mental health care use and suicidal behaviour. Better physical and mental functioning before depression onset predicted shorter duration. Among MinDD cases, shorter median duration (3 months) but similar mean duration (8.7 months), risk of chronicit...Continue Reading

References

Nov 1, 1995·Psychological Medicine·R RamanaP G Surtees
Sep 3, 2002·The British Journal of Psychiatry : the Journal of Mental Science·Jan SpijkerWillem A Nolen
Jun 19, 2003·JAMA : the Journal of the American Medical Association·Ronald C KesslerUNKNOWN National Comorbidity Survey Replication
Aug 5, 2004·The Journal of Clinical Psychiatry·Tarja K MelartinErkki T Isometsä
Aug 7, 2004·International Journal of Methods in Psychiatric Research·Ronald C Kessler, T Bedirhan Ustün
Oct 9, 2007·Journal of Affective Disorders·David A SolomonMartin B Keller
Feb 7, 2008·The Journal of Clinical Psychiatry·K Mikael HolmaErkki T Isometsä
May 7, 2008·Archives of General Psychiatry·William W EatonPeter Zandi
Mar 3, 2009·Psychological Medicine·M S VuorilehtoE T Isometsä
Jan 16, 2010·Journal of Affective Disorders·Peter de JongeJohan Ormel
Jul 20, 2010·International Journal of Methods in Psychiatric Research·Ron de GraafSaskia van Dorsselaer
Apr 19, 2011·Journal of Affective Disorders·Brenda W J H PenninxAartjan T F Beekman
Jul 28, 2011·BMC Medicine·Evelyn BrometRonald C Kessler
Jan 10, 2014·Social Psychiatry and Psychiatric Epidemiology·Esme Fuller-ThomsonSarah Brennenstuhl
Oct 21, 2015·Journal of Affective Disorders·Scott B PattenJianLi Wang
Nov 8, 2015·Journal of Affective Disorders·Margreet Ten HaveRon de Graaf

❮ Previous
Next ❯

Citations

May 30, 2020·European Psychiatry : the Journal of the Association of European Psychiatrists·Dominik A MoserDaniel S Schechter
Mar 27, 2018·Acta Psychiatrica Scandinavica·M Ten HaveB W J H Penninx
May 23, 2020·Neuropsychiatric Disease and Treatment·Carlotta LunghiElisabetta Poluzzi
Apr 30, 2020·International Journal of Molecular Sciences·Mike C JentschRobert A Schoevers
Apr 21, 2020·Work : a Journal of Prevention, Assessment, and Rehabilitation·Cecilie N ThistedMerete B Bjerrum
Dec 29, 2020·Journal of Cardiac Failure·Kenneth E FreedlandMichael W Rich
Feb 16, 2021·Journal of Affective Disorders·Wendela G Ter MeulenBrenda W J H Penninx
Nov 24, 2020·Indian Journal of Psychiatry·Shokhrukh SultanovLola Shadmanova
Mar 6, 2021·BMC Psychiatry·Farrokh AlemiAndrew A Nierenberg
Sep 1, 2021·European Psychiatry : the Journal of the Association of European Psychiatrists·R C Oude VoshaarH W Jeuring
Nov 12, 2021·Epidemiology and Psychiatric Sciences·Annelieke M RoestUNKNOWN WHO World Mental Health Survey collaborators

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.