Duration of Reproductive Years and the Risk of Cardiovascular and Cerebrovascular Events in Older Women: Insights from the National Health and Nutrition Examination Survey

Journal of Women's Health
Hend MansoorAbraham Hartzema

Abstract

Studies have shown conflicting information regarding the association between the age at menarche and/or menopause and cardiovascular and cerebrovascular diseases in older women. This study aimed to determine whether a longer duration of reproductive years in older women in the U.S. population was associated with a lower risk of cardiovascular and cerebrovascular diseases. Women ≥60 years who participated in the National Health and Nutrition Examination Survey from 2007 to 2012 were included. Subjects provided information about the age of menarche and menopause along with the presence/absence of cardiovascular and cerebrovascular diseases. Participants were categorized into either a longer reproductive duration group (>30 years) or shorter reproductive duration group (≤30 years). Subgroup analysis for each 5-year increment in the longer reproductive duration group was conducted. Relative risk (RR) regression was performed using a generalized linear model adjusting for several confounding factors. 3081 participants were included in the analysis. A longer duration of reproductive years was associated with a lower risk of cardiovascular and cerebrovascular diseases, compared with a shorter duration (RR 0.70, 95% confidence interval...Continue Reading

References

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Citations

Dec 11, 2019·Journal of the American Heart Association·Hend MansoorArch G Mainous
Oct 15, 2019·The Journal of Cardiovascular Nursing·Lola A Coke, Cheryl Dennison-Himmelfarb
Dec 15, 2017·Journal of Women's Health·Yon Chul ParkJong-Koo Kim
Jul 20, 2019·TheScientificWorldJournal·Luciane Maria Oliveira BritoIsmael Dale Cotrim Guerreiro da Silva
Jan 1, 2021·International Journal of Environmental Research and Public Health·Eun Young ParkJong Koo Kim

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Methods Mentioned

BETA
hormone replacement therapy

Software Mentioned

SAS

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