Duration of viral shedding in asymptomatic or mild cases of novel coronavirus disease 2019 (COVID-19) from a cruise ship: A single-hospital experience in Tokyo, Japan

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Yuka MiyamaeKoji Ishii

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the cause of novel coronavirus disease 2019 (COVID-19), was first reported in Wuhan, China, and now has spread across the world as a global pandemic. The propagation from asymptomatic polymerase chain reaction (PCR)-positive individuals represents a complicating factor in the efforts to control the COVID-19 pandemic. We examined the course of PCR assays and the duration of viral shedding in 23 asymptomatic or mild COVID-19 patients from the cruise ship who were admitted to our hospital. Among these 23 cases, the median duration of viral shedding was 19 days (range, 6-37 days) from initial viral detection. Eight cases (35%) had another positive PCR result after testing negative once. Although the duration of viral shedding was approximately three weeks, the infectivity and transmissibility period from asymptomatic and mild COVID-19 cases is unclear. Further studies are needed to determine how long such asymptomatic and mild COVID-19 cases have infectivity.

Citations

Jul 12, 2020·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Kiran Gajurel
Oct 9, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Chanu RheeMichael Klompas
Oct 21, 2020·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Lauren M FontanaJessina C McGregor
Dec 21, 2020·Journal of Infection and Public Health·Jumana Mansour AlJishiJaffar A Al-Tawfiq
Dec 6, 2020·Current Opinion in Pediatrics·Paul Spearman
Jun 3, 2021·International Journal of Environmental Research and Public Health·Ann-Christin KordsmeyerMarcus Oldenburg
Jun 18, 2021·PloS One·Susan P PhillipsPatti A Groome
Jul 1, 2021·Indoor Air·Patrick F HorveKevin G Van Den Wymelenberg

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