DWARF 53 acts as a repressor of strigolactone signalling in rice

Nature
Liang JiangJiayang Li

Abstract

Strigolactones (SLs) are a group of newly identified plant hormones that control plant shoot branching. SL signalling requires the hormone-dependent interaction of DWARF 14 (D14), a probable candidate SL receptor, with DWARF 3 (D3), an F-box component of the Skp-Cullin-F-box (SCF) E3 ubiquitin ligase complex. Here we report the characterization of a dominant SL-insensitive rice (Oryza sativa) mutant dwarf 53 (d53) and the cloning of D53, which encodes a substrate of the SCF(D3) ubiquitination complex and functions as a repressor of SL signalling. Treatments with GR24, a synthetic SL analogue, cause D53 degradation via the proteasome in a manner that requires D14 and the SCF(D3) ubiquitin ligase, whereas the dominant form of D53 is resistant to SL-mediated degradation. Moreover, D53 can interact with transcriptional co-repressors known as TOPLESS-RELATED PROTEINS. Our results suggest a model of SL signalling that involves SL-dependent degradation of the D53 repressor mediated by the D14-D3 complex.

References

Apr 1, 1968·Experimental Cell Research·O L GamborgK Ojima
Jan 22, 2005·Plant & Cell Physiology·Shinji IshikawaJunko Kyozuka
Jun 10, 2006·Science·Jeff A LongElliot M Meyerowitz
Dec 13, 2006·Plant Physiology·Joanne L SimonsKimberley C Snowden
Mar 10, 2007·The Plant Journal : for Cell and Molecular Biology·Petra StirnbergH M Ottoline Leyser
Jul 28, 2007·The Plant Journal : for Cell and Molecular Biology·Tomotsugu AriteJunko Kyozuka
May 1, 2008·Annual Review of Plant Biology·Yonghong Wang, Jiayang Li
Aug 12, 2008·Nature·Mikihisa UmeharaShinjiro Yamaguchi
Aug 12, 2008·Nature·Victoria Gomez-RoldanSoizic F Rochange
May 21, 2009·The Plant Journal : for Cell and Molecular Biology·Daniel KierzkowskiArtur Jarmolowski
Jun 23, 2009·Plant & Cell Physiology·Tomotsugu AriteJunko Kyozuka
Jul 16, 2009·Plant Molecular Biology·Zhenyu GaoBin Han
Apr 3, 2010·Nature·Laurens PauwelsAlain Goossens
Mar 24, 2011·Nature Reviews. Molecular Cell Biology·Malgorzata A Domagalska, Ottoline Leyser
May 11, 2011·Proceedings of the National Academy of Sciences of the United States of America·David C NelsonSteven M Smith
Jul 12, 2011·Bioorganic & Medicinal Chemistry Letters·Kosuke FukuiTadao Asami
Nov 9, 2011·Plant Physiology·Barry CausierBrendan Davies
Mar 17, 2012·Science·Adrian AlderSalim Al-Babili
Nov 10, 2012·Current Biology : CB·Steven M Smith, Mark T Waters
Nov 28, 2012·Trends in Plant Science·Carolien Ruyter-SpiraHarro Bouwmeester
Jan 11, 2013·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Megumi KagiyamaToshio Hakoshima

❮ Previous
Next ❯

Citations

Jul 19, 2014·PloS One·Olaf CzarneckiJin-Gui Chen
Sep 3, 2014·Current Opinion in Plant Biology·Tom Bennett, Ottoline Leyser
Jul 20, 2014·Trends in Plant Science·Hinanit Koltai
Jul 2, 2014·Current Opinion in Plant Biology·Yoshiya Seto, Shinjiro Yamaguchi
Jul 6, 2014·Current Opinion in Plant Biology·Steven M Smith, Jiayang Li
Dec 2, 2014·Journal of Genetics and Genomics = Yi Chuan Xue Bao·Xiaoming LiXuelu Wang
Apr 5, 2014·Nature Structural & Molecular Biology·Nitzan Shabek, Ning Zheng
Mar 13, 2014·Plant Cell Reports·Kang Chong, Zhihong Xu
Jan 1, 2015·Plants·Yusuke Yamada, Mikihisa Umehara
Dec 17, 2015·Critical Reviews in Biotechnology·Abdullah MakhzoumJocelyne Tremouillaux-Guiller
Nov 27, 2014·Proceedings of the National Academy of Sciences of the United States of America·Satoko AbeTakahito Nomura
Feb 4, 2016·Planta·Binne ZwanenburgSanja Ćavar Zeljković
Dec 4, 2015·Proceedings of the National Academy of Sciences of the United States of America·Lei WangQifa Zhang
Oct 28, 2015·Journal of Natural Products·Emma ArtusoCristina Prandi
Dec 9, 2014·Plant Signaling & Behavior·Jieru LiLi-Jia Qu
Sep 29, 2015·Journal of Agricultural and Food Chemistry·Oussama AhrazemLourdes Gómez-Gómez
Apr 20, 2016·Frontiers in Plant Science·Amita PandeyGirdhar K Pandey
Sep 1, 2015·Frontiers in Plant Science·Kanako MitsumasuSatoko Yoshida
Jul 3, 2015·Journal of Experimental Botany·Elisabeth StesDanny Vereecke
Apr 23, 2015·Journal of Experimental Botany·Hinanit Koltai
Apr 19, 2015·Annals of Botany·Huwei SunYali Zhang
Jan 27, 2015·Annual Review of Plant Biology·Salim Al-Babili, Harro J Bouwmeester
Jan 30, 2015·Frontiers in Plant Science·Catherine RameauSoulaiman Sakr
Nov 22, 2014·Frontiers in Plant Science·Hidemitsu Nakamura, Tadao Asami
May 20, 2016·Proceedings of the National Academy of Sciences of the United States of America·Philip B BrewerChristine A Beveridge
Oct 30, 2016·Proceedings of the National Academy of Sciences of the United States of America·Hongju ZhouJiayang Li
Feb 16, 2016·Scientific Reports·Kaijie ZhengJin-Gui Chen
Aug 28, 2015·Plant Physiology and Biochemistry : PPB·Chao WenLiangjun Zhao
Apr 11, 2017·Current Biology : CB·Eva-Sophie WallnerThomas Greb
Jan 27, 2017·Annual Review of Plant Biology·Mark T WatersDavid C Nelson
May 18, 2017·Nature Chemical Biology·Shelley LumbaPeter McCourt
Apr 13, 2017·Trends in Plant Science·Juan A López-RáezEloise Foo
Mar 30, 2017·Science China. Life Sciences·Lan ShenKejian Wang
Apr 19, 2017·Bioscience, Biotechnology, and Biochemistry·Takuya Miyakawa, Masaru Tanokura

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.