PMID: 3627562Aug 5, 1987

Dye and electrotonic coupling between cultured hippocampal neurons

Neuroscience Letters
M O'BeirneB A MacVicar

Abstract

Electrotonic coupling was examined between hippocampal neurons in dissociated cell cultures. Injections of Lucifer yellow indicated that approximately 20% of the neurons were dye-coupled. Propionate, which causes cytoplasmic acidification, significantly decreased dye coupling. Simultaneous intracellular recordings from pairs of cultured neurons directly demonstrated electrotonic coupling. Therefore dissociated cell cultures can be used as a model system for the analysis of hippocampal electrotonic coupling.

References

Mar 18, 1985·Brain Research·B A MacVicar, H Jahnsen
Oct 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·J A KesslerM V Bennett
Feb 1, 1982·Brain Research Bulletin·R D AndrewF E Dudek
Sep 8, 1980·Brain Research·B A MacVicar, F E Dudek
Apr 22, 1982·Brain Research·B A MacVicarK Krnjevic
Sep 1, 1981·Bioscience Reports·R Iles
Dec 1, 1984·Journal of Neuroscience Methods·B A MacVicar
Mar 1, 1981·The Journal of Physiology·A P Sharp, R C Thomas

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