Dye-sensitized photooxidation of the Escherichia coli ribosome

Science
R T GarvinS J Rogers

Abstract

Chemical modification of ribosomes from Escherichia coli by oxidation in the presence of selected photosensitizing dyes causes a rapid loss of their amino acid-incorporating ability. By comparing the efficiency of dyes that sensitize the photooxidation of either guanine in ribonucleic acid or amino acid residues in proteins, inactivation of one or more functional ribosomal proteins is inferred.

References

Jul 1, 1967·European Journal of Biochemistry·R R Traut, A L Haenni
Jan 1, 1968·Annual Review of Biochemistry·S Osawa
Jan 1, 1968·Archives of Biochemistry and Biophysics·J S Bellin, C A Yankus
Sep 10, 1968·Archives of Biochemistry and Biophysics·T R Hopkins, J D Spikes
Jan 1, 1965·Photochemistry and Photobiology·J S Bellin, L I Grossman
Jul 1, 1966·Biochemistry·B Singer, H Fraenkel-Conrat
Oct 1, 1953·Archives of Biochemistry and Biophysics·L WEILA R BUCHERT
Nov 1, 1951·Archives of Biochemistry and Biophysics·L WEIL, A R BUCHERT

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Citations

Jan 1, 1979·Pharmacology & Therapeutics·L E BockstahlerJ E Roberts
Oct 15, 1975·European Journal of Biochemistry·K K WanR M Baxter
Sep 1, 1970·The Journal of Clinical Pharmacology and the Journal of New Drugs·C E ShieldsN I Birndorf
Jun 15, 1979·FEBS Letters·J Cerná, I Rychlík
Dec 1, 1976·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·S Nishiyama-Watanabe
Feb 1, 1985·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·G B CastellanosL R Caldas
Jun 2, 2015·Scientific Reports·Sahabudeen Sheik MohideenYuji Yoshiike
May 23, 1976·Biochemical and Biophysical Research Communications·H Singh, J A Vadasz
Feb 24, 1976·Biochemistry·C L Pon, C Gualerzi
Sep 24, 2019·Future Medicinal Chemistry·Michael R Hamblin, Heidi Abrahamse
Sep 1, 1970·Bacteriological Reviews·M Nomura

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