Dying of gamma-irradiated Escherichia coli studied by the use of prophage.

Journal of Bacteriology
D PetranovićZ Trgovcević

Abstract

Loss of the biological activity of deoxyribonucleic acid in gamma-irradiated Escherichia coli cells was studied. The study is based on two sets of experimental data: (i) post-irradiation heat inducibility of the cells whose chromosomes were "labeled" with the thermoinducible lambdacI857ind prophage, and (ii) post-irradiation capacity of nonlysogenic cells to promote growth of the unirradiated lambdacI857ind phage. The results show that, at the beginning of incubation after irradiation, the number of plaques formed upon heat induction of lysogenic cells was much higher than the viable cell count of the nonheated culture. This high resistance of the heat inducibility gradually decreased during post-irradiation incubation. Finally, after a period of 4 h, there was no difference in sensitivity between the heat inducibility and the colony-forming ability of gamma-irradiated cells. The capacity of gamma-irradiated bacteria to support growth of unirradiated lambdacI857ind is radioresistant; this resistance, in contrast to that of heat inducibility, is much less affected during post-irradiation incubation. A continuous decrease in radioresistance of heat inducibility without a corresponding decrease in radioresistance of the capacity s...Continue Reading

References

Jun 28, 1972·Journal of Molecular Biology·T Noguti, T Kada
Nov 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·P J Laipis, A T Ganesan
Jan 1, 1968·Annual Review of Biochemistry·P Howard-Flanders
May 7, 1971·Biochemical and Biophysical Research Communications·Z TrgovcevićV Zgaga
Jul 15, 1965·Biochimica Et Biophysica Acta·D BillenG Jorgensen
Apr 7, 1961·Biochemical and Biophysical Research Communications·B MILETICL ZAJEC

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Citations

Jan 1, 1979·Molecular & General Genetics : MGG·E Salaj-SmicZ Trgovcević
Aug 1, 1991·Molecular & General Genetics : MGG·K Brcić-KostićZ Trgovcević
Jan 1, 1984·Molecular & General Genetics : MGG·M PetranovićZ Trgovcević
Dec 1, 1989·Mutation Research·K Brcić-KostićZ Trgovcević
Jul 1, 1987·Mutation Research·Z TrgovcevićM Petranović
Feb 1, 1992·Mutation Research·K Brcić-KostićZ Trgovcević

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