Dynamic air/liquid pockets for guiding microscale flow

Nature Communications
Xu HouJoanna Aizenberg

Abstract

Microscale flows of fluids are mainly guided either by solid matrices or by liquid-liquid interfaces. However, the solid matrices are plagued with persistent fouling problems, while liquid-liquid interfaces are limited to low-pressure applications. Here we report a dynamic liquid/solid/gas material containing both air and liquid pockets, which are formed by partially infiltrating a porous matrix with a functional liquid. Using detailed theoretical and experimental data, we show that the distribution of the air- and liquid-filled pores is responsive to pressure and enables the formation and instantaneous recovery of stable liquid-liquid interfaces that sustain a wide range of pressures and prevent channel contamination. This adaptive design is demonstrated for polymeric materials and extended to metal-based systems that can achieve unmatched mechanical and thermal stability. Our platform with its unique adaptive pressure and antifouling capabilities may offer potential solutions to flow control in microfluidics, medical devices, microscale synthesis, and biological assays.

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Citations

Apr 11, 2019·Electrophoresis·Jian ZhangXu Hou
Jul 27, 2020·Chemical Society Reviews·Zhizhi ShengXu Hou
Sep 19, 2020·Engineering in Life Sciences·Akari NishigakiKazufumi Takano
Oct 5, 2018·Nature Communications·B FanP R Bandaru
Jan 30, 2020·ACS Nano·Alexander B TeslerXu Hou
Feb 28, 2021·Nature Communications·Sangjin SeoTaesung Kim
Apr 10, 2021·Advanced Materials·Jian ZhangXu Hou
Nov 11, 2020·Analytical Chemistry·Simon F BerlandaPetra S Dittrich
Feb 28, 2020·ACS Applied Materials & Interfaces·Kousik MajiUttam Manna
Jul 3, 2018·ACS Nano·Yifan SiLei Jiang
Jan 5, 2022·Langmuir : the ACS Journal of Surfaces and Colloids·Arvind Arun DevBernard Doudin

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Methods Mentioned

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scanning electron microscopy

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