PMID: 8308Jan 1, 1976

Dynamic asymmetries in liver tyrosine aminotransferase induction

Enzyme
M Stefan, N Gheorghe

Abstract

Changes in liver tyrosine aminotransferase activity were measured in mice and rats following a whole body X-irradiation in order to ascertain the dose-effect relationship. The response was either (1) linear in case of low pulses (25 rad/min); (2) parabolic, indicating the onset of a saturation process in case of medium pulses (60 rad/min), or (3) biphasic, suggesting the cooperation of at least two regulatory mechanisms following longtime exposure to strong stimuli (100 rad/min).

Related Concepts

Adrenalectomy
Dose-Response Relationship, Drug
Dose-Response Relationship, Radiation
Enzyme Induction
Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer
Liver
Effects of Radiation
Tyrosine Aminotransferase
Roentgen Rays

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