PMID: 9159627May 1, 1997Paper

Dynamic cardiac compression improves contractile efficiency of the heart

The Journal of Thoracic and Cardiovascular Surgery
O KawaguchiH Suga

Abstract

The effect of dynamic cardiac compression on left ventricular contractile efficiency was assessed in terms of the pressure-volume relationship and myocardial oxygen consumption. In 11 excised cross-circulated dog hearts, the ventricle was directly compressed during systole (dynamic cardiac compression). Measurements for pressure-volume area (a measure of total mechanical energy), external work, and myocardial oxygen consumption were done before and during dynamic cardiac compression. Dynamic cardiac compression increased pressure-volume area by 28% +/- 17% (mean plus or minus the standard deviation) and external work by 24% +/- 20% (p = 0.0000185 and 0.0000212, respectively) at given end-diastolic and stroke volumes without affecting myocardial oxygen consumption. As a result, the oxygen cost of pressure-volume area, that is, the slope of the myocardial oxygen consumption-pressure-volume area relationship, significantly decreased by 16% +/- 13% (p = 0.0000135) whereas the pressure-volume area-independent myocardial oxygen consumption was unchanged. Then, contractile efficiency, that is, the reciprocal of the slope of the myocardial oxygen consumption-pressure-volume area relationship in joules significantly improved from 45% +/...Continue Reading

References

Jan 1, 1992·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·J C ChachquesA Carpentier
Oct 1, 1994·Circulation·R M el Oakley, J C Jarvis
Feb 1, 1994·The Annals of Thoracic Surgery·H NakajimaR Fietsam
Jul 1, 1993·The Annals of Thoracic Surgery·R RuggieroH O Nakajima
Jul 1, 1993·The Annals of Thoracic Surgery·P W ChoM A Acker

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Citations

Jan 13, 2001·The Annals of Thoracic Surgery·K ShirotaS N Hunyor
Feb 16, 2002·The Annals of Thoracic Surgery·Mark P AnstadtYukihiko Nosé
Jan 23, 2003·The Annals of Thoracic Surgery·Russell A J CarringtonStephen N Hunyor
Oct 26, 2002·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Mehmet C OzDaniel Burkhoff
Dec 8, 2000·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·S V PuscaM A Acker
Jan 29, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Paris D KalogerakosVlassis S Ladopoulos
Jun 17, 1998·The Journal of Thoracic and Cardiovascular Surgery·O KawaguchiS N Hunyor
Jun 3, 1999·Circulation·D R TrumbleJ A Magovern
Apr 28, 2017·PLoS Computational Biology·David J AlbersLena Mamykina

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