Dynamic change of depression and anxiety after chemotherapy among patients with ovarian cancer

Medicine
Hongxia Liu, Linqing Yang

Abstract

Psychological state of patients with ovarian cancer is worthy of attention. We aimed to investigate the levels of anxiety and depression in patients with ovarian cancer. We also investigated the dynamic changes in anxiety and depression levels after chemotherapy.A total of 228 females were included in this study. Among them, a total of 111 participants had ovarian cancer and 117 females who underwent a physical examination were selected as healthy controls. All patients enrolled were asked to fill in the Self-rating Depression Scale and the Self-rating Anxiety Scale. For patients with ovarian cancer, repeat questionnaires were measured after cycle 1 chemotherapy.The depression score of patients with ovarian cancer was 45.90 ± 10.19, significantly higher than in controls (36.08 ± 9.06, P < .001). Similar results were observed in respect of anxiety score. The score of ovarian cancer patients was 39.53 ± 12.92, significantly higher than of controls (32.15 ± 7.44, P < .001). Multivariate analyses were conducted, and the results showed that young age was the independent risk factor associated with depression among patients with ovarian cancer, while young age and singleness were the independent risk factors associated with anxiety. ...Continue Reading

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Citations

Jun 20, 2020·Journal of Psychosomatic Research·Andrea A CoheeShelley A Johns
May 13, 2021·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Li-Hua YangXiao-Qing Wang
Jun 28, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Kate OppegaardChristine Miaskowski

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